Products Categories
| CAS No.: | 62720-29-0 |
|---|---|
| Name: | 1,3-Dibromo-5-fluoro-2-iodobenzene |
| Article Data: | 1 |
| Molecular Structure: | |
|
|
|
| Formula: | C6H2Br2FI |
| Molecular Weight: | 379.793 |
| Synonyms: | 1,3-Dibromo-5-fluoro-2-iodobenzene; |
| Density: | 2.564 g/cm3 |
| Melting Point: | 134-137 °C |
| Boiling Point: | 292.8 °C at 760 mmHg |
| Flash Point: | 130.9 °C |
| Appearance: | beige to pinkish or pale brown |
| Hazard Symbols: |
 Xi
|
| Risk Codes: | 36/37/38 |
| Safety: | 24/25 |
| PSA: | 0.00000 |
| LogP: | 3.95530 |
- 81281-59-67-Benzylideneaminotheophylline
- 82993-81-5D-threo-Ritalinic acid hydrochloride
- 73441-42-6METHYL-5-CHLORO-2,2-DIMETHYLVALERATE
- 68439-39-4Poly(oxy-1,2-ethanediyl), alpha-(2-ethylhexyl)-omega-hydroxy-,
- 852475-26-4MC1568
- 958254-66-51H-Imidazo[4,5-b]pyridine-2-carboxaldehyde, 1-methyl-, hydrochloride
- 99170-93-1N-Methyl-2-oxazolamine
- 717878-06-31-(4-fluorophenyl)-4-nitro-1H-imidazole
- 914458-26-7[5-(2-fluorophenyl)-1-pentyl-1H-pyrrol-3-yl]-1-naphthalenyl-Methanone
- 894852-01-87-BROMO-2,2-DIMETHYL-2H-PYRIDO[3,2-B][1,4]OXAZIN-3(4H)-ONE
- 401631-93-4
C10H12Br2FN3
- 62720-29-0
1,3-dibromo-2-iodo-5-fluorobenzene
| Conditions | Yield |
|---|---|
| With hydrogen iodide In acetonitrile at 60℃; for 1.5h; | 71% |
- 344-18-3
2,6-dibromo-4-fluoroaniline
- 62720-29-0
1,3-dibromo-2-iodo-5-fluorobenzene
| Conditions | Yield |
|---|---|
| Multi-step reaction with 3 steps 1: 98 percent / i-pentyl nitrite; HOAc / 0 - 5 °C 2: 95 percent / aq. NaOH / 0.5 h / 0 - 5 °C 3: 71 percent / aq. HI / acetonitrile / 1.5 h / 60 °C View Scheme |
- 62720-29-0
1,3-dibromo-2-iodo-5-fluorobenzene
| Conditions | Yield |
|---|---|
| Multi-step reaction with 2 steps 1: 95 percent / aq. NaOH / 0.5 h / 0 - 5 °C 2: 71 percent / aq. HI / acetonitrile / 1.5 h / 60 °C View Scheme |
- 62720-29-0
1,3-dibromo-2-iodo-5-fluorobenzene
- 870-63-3
prenyl bromide
| Conditions | Yield |
|---|---|
| Stage #1: 1,3-dibromo-5-fluoro-2-iodobenzene With isopropylmagnesium chloride In tetrahydrofuran at -20 - 0℃; for 1h; Inert atmosphere; Stage #2: prenyl bromide With copper(l) iodide In tetrahydrofuran at 0 - 20℃; | 85% |
- 62720-29-0
1,3-dibromo-2-iodo-5-fluorobenzene
- 1204-55-3
thioacetic acid S-(2-acetylamino-phenyl)ester
| Conditions | Yield |
|---|---|
| With caesium carbonate In N,N-dimethyl-formamide at 130℃; for 10h; Inert atmosphere; | 65% |
- 62720-29-0
1,3-dibromo-2-iodo-5-fluorobenzene
- 98-80-6
phenylboronic acid
- 1383568-74-8
2,6-dibromo-4-fluorobiphenyl
| Conditions | Yield |
|---|---|
| Stage #1: 1,3-dibromo-5-fluoro-2-iodobenzene With [1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene](3-chloropyridyl)palladium(II) dichloride; potassium carbonate In 1,4-dioxane at 20℃; for 1h; Suzuki-Miyaura coupling; Inert atmosphere; Stage #2: phenylboronic acid In 1,4-dioxane for 36h; Suzuki-Miyaura coupling; Inert atmosphere; Reflux; | 58% |
- 62720-29-0
1,3-dibromo-2-iodo-5-fluorobenzene
- 68-12-2, 33513-42-7
N,N-dimethyl-formamide
- 938467-02-8
2,6-dibromo-4-fluorobenzaldehyde
| Conditions | Yield |
|---|---|
| Stage #1: 1,3-dibromo-5-fluoro-2-iodobenzene With isopropylmagnesium chloride In diethyl ether; toluene at -35 - -25℃; for 2h; Stage #2: N,N-dimethyl-formamide In diethyl ether; toluene at -19 - 10℃; for 2h; Product distribution / selectivity; | 54% |
| Stage #1: 1,3-dibromo-5-fluoro-2-iodobenzene With isopropylmagnesium chloride In diethyl ether; toluene at -35 - -25℃; for 2h; Stage #2: N,N-dimethyl-formamide In diethyl ether; toluene at -19 - 10℃; for 2h; | 54% |
| Stage #1: 1,3-dibromo-5-fluoro-2-iodobenzene With isopropylmagnesium chloride In ethyl acetate; toluene at -35 - -25℃; for 2h; Stage #2: N,N-dimethyl-formamide In ethyl acetate; toluene at 10 - 20℃; for 3h; | 54% |
| Stage #1: 1,3-dibromo-5-fluoro-2-iodobenzene With isopropylmagnesium chloride In diethyl ether; toluene at -35 - -25℃; for 1.5h; Stage #2: N,N-dimethyl-formamide In diethyl ether; toluene at -19 - 10℃; for 1.5h; | 54% |
| Stage #1: 1,3-dibromo-5-fluoro-2-iodobenzene With isopropylmagnesium chloride In tetrahydrofuran; toluene at -35 - -25℃; for 2h; Stage #2: N,N-dimethyl-formamide In tetrahydrofuran; toluene at -35 - 20℃; for 1.5h; | 49% |
- 62720-29-0
1,3-dibromo-2-iodo-5-fluorobenzene
- 1068-55-9
isopropylmagnesium chloride
- 68-12-2, 33513-42-7
N,N-dimethyl-formamide
- 938467-02-8
2,6-dibromo-4-fluorobenzaldehyde
| Conditions | Yield |
|---|---|
| Stage #1: 1,3-dibromo-5-fluoro-2-iodobenzene; isopropylmagnesium chloride In diethyl ether; toluene at -35 - -25℃; for 2h; Stage #2: N,N-dimethyl-formamide In diethyl ether; toluene at -19 - 10℃; for 3h; | 54% |
- 62720-29-0
1,3-dibromo-2-iodo-5-fluorobenzene
- 1435-51-4
1,3-dibromo-5-fluorobenzene
| Conditions | Yield |
|---|---|
| With isopropylmagnesium chloride In tetrahydrofuran; toluene at -35 - -25℃; for 2h; Inert atmosphere; |
- 62720-29-0
1,3-dibromo-2-iodo-5-fluorobenzene
- 68-12-2, 33513-42-7
N,N-dimethyl-formamide
A
- 938467-02-8
2,6-dibromo-4-fluorobenzaldehyde
B
- 1435-51-4
1,3-dibromo-5-fluorobenzene
| Conditions | Yield |
|---|---|
| Stage #1: 1,3-dibromo-5-fluoro-2-iodobenzene With isopropylmagnesium chloride In tetrahydrofuran Inert atmosphere; Stage #2: N,N-dimethyl-formamide In tetrahydrofuran; water Inert atmosphere; |
What can I do for you?
Get Best Price
Specification
The Benzene,1,3-dibromo-5-fluoro-2-iodo-, with CAS registry number 62720-29-0, belongs to the following product categories: (1)Bromine Compounds; (2)Fluorine Compounds; (3)Iodine Compounds. It has the systematic name of 1,3-dibromo-5-fluoro-2-iodobenzene. This chemical is a kind of beige to pinkish or pale brown.
Physical properties of Benzene,1,3-dibromo-5-fluoro-2-iodo-: (1)ACD/LogP: 4.53; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 4.53; (4)ACD/LogD (pH 7.4): 4.53; (5)ACD/BCF (pH 5.5): 1643.07; (6)ACD/BCF (pH 7.4): 1643.07; (7)ACD/KOC (pH 5.5): 6972.13; (8)ACD/KOC (pH 7.4): 6972.13; (9)#H bond acceptors: 0; (10)#H bond donors: 0; (11)#Freely Rotating Bonds: 0; (12)Polar Surface Area: 0 Å2; (13)Index of Refraction: 1.657; (14)Molar Refractivity: 54.53 cm3; (15)Molar Volume: 148 cm3; (16)Polarizability: 21.61×10-24cm3; (17)Surface Tension: 48.6 dyne/cm; (18)Enthalpy of Vaporization: 51.1 kJ/mol; (19)Vapour Pressure: 0.00313 mmHg at 25°C.
Preparation: this chemical can be prepared by C10H12Br2FN3. This reaction will need reagent aq. HI and solvent acetonitrile. The reaction time is 90 min with reaction temperature of 60 ℃. The yield is about 71%.
.jpg)
When you are using this chemical, please be cautious about it as the following:
The Benzene,1,3-dibromo-5-fluoro-2-iodo- irritates to eyes, respiratory system and skin. When use this chemical, avoid contact with skin and eyes.
You can still convert the following datas into molecular structure:
(1)SMILES: Brc1cc(F)cc(Br)c1I
(2)InChI: InChI=1/C6H2Br2FI/c7-4-1-3(9)2-5(8)6(4)10/h1-2H
(3)InChIKey: LIWKANDEJFABTQ-UHFFFAOYAW
(4)Std. InChI: InChI=1S/C6H2Br2FI/c7-4-1-3(9)2-5(8)6(4)10/h1-2H
(5)Std. InChIKey: LIWKANDEJFABTQ-UHFFFAOYSA-N