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63470-85-9

Basic Information
CAS No.: 63470-85-9
Name: 2-methoxy-N-[2-nitro-5-(phenylthio)phenyl]acetamide
Article Data: 4
Molecular Structure:
Molecular Structure of 63470-85-9 (2-methoxy-N-[2-nitro-5-(phenylthio)phenyl]acetamide)
Formula: C15H14 N2 O4 S
Molecular Weight: 318.353
Synonyms: 2-methoxy-N-[2-nitro-5-(phenylthio)phenyl]acetamide
Density: 1.35g/cm3
Boiling Point: 551.7°C at 760 mmHg
Flash Point: 287.5°C
PSA: 112.94000
LogP: 4.50360
Synthetic route
6290-49-9

methyl methoxyacetate

43156-47-4

2-nitro-5-phenylthioaniline

63470-85-9

2-methoxy-N-(2-nitro-5-(phenylsulfanyl)phenyl)acetamide

Conditions
ConditionsYield
at 120 - 130℃; Temperature;95.5%
43156-47-4

2-nitro-5-phenylthioaniline

625-45-6

2-methoxyacetic acid

63470-85-9

2-methoxy-N-(2-nitro-5-(phenylsulfanyl)phenyl)acetamide

Conditions
ConditionsYield
With pyridine; thionyl chloride In toluene at 75 - 110℃; for 10.5h; Reagent/catalyst; Solvent; Temperature;94.8%
108-86-1

bromobenzene

63470-85-9

2-methoxy-N-(2-nitro-5-(phenylsulfanyl)phenyl)acetamide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: potassium carbonate / 150 - 160 °C / Inert atmosphere
2: 120 - 130 °C
View Scheme

2-amino-4-mercapto-1-nitrobenzene

63470-85-9

2-methoxy-N-(2-nitro-5-(phenylsulfanyl)phenyl)acetamide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: potassium carbonate / 130 - 135 °C / Inert atmosphere
2: 120 - 130 °C
View Scheme
108-90-7

chlorobenzene

63470-85-9

2-methoxy-N-(2-nitro-5-(phenylsulfanyl)phenyl)acetamide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: potassium carbonate / 130 - 135 °C / Inert atmosphere
2: 120 - 130 °C
View Scheme
63470-85-9

2-methoxy-N-(2-nitro-5-(phenylsulfanyl)phenyl)acetamide

58306-67-5

2-amino-5-phenylthio-(2-methoxy)acetanilide

Conditions
ConditionsYield
With hydrogen In methanol at 25 - 35℃; under 750.075 - 3750.38 Torr; for 12h; Temperature; Solvent; Autoclave;94.2%
With hydrogen; nickel In chlorobenzene at 35 - 55℃; under 22065.2 - 36775.4 Torr;
With hydrogen; nickel In 1,2-dichloro-benzene at 40 - 50℃; under 22065.2 - 36775.4 Torr;
63470-85-9

2-methoxy-N-(2-nitro-5-(phenylsulfanyl)phenyl)acetamide

2-Methoxy-N-{2-[2-(2-methoxy-acetylamino)-5-phenylsulfanyl-phenyl-NNO-azoxy]-5-phenylsulfanyl-phenyl}-acetamide

Conditions
ConditionsYield
With hydrogen; nickel In tetrahydrofuran at 30 - 40℃; under 36775.4 Torr;
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