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CAS No.: | 63717-27-1 |
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Name: | Amifostine hydrate |
Molecular Structure: | |
Formula: | C5H15N2O3PS.H2O |
Molecular Weight: | 232.23800 |
Synonyms: | Amifostine hydrate;Amifostinum;Amifostina;amifostine monohydrate; |
Melting Point: | 160-161° (dec) |
Boiling Point: | 441.7oC at 760 mmHg |
Flash Point: | 220.9oC |
PSA: | 139.92000 |
LogP: | 0.77760 |
IUPAC Name: 2-(3-Aminopropylamino)ethylsulfanylphosphonic acid hydrate
The molecular formula of Amifostine hydrate (CAS NO.63717-27-1) is C5H17N2O4PS.
The molecular weight of Amifostine hydrate (CAS NO.63717-27-1) is 232.24.
Synonyms of Amifostine hydrate (CAS NO.63717-27-1): Ethanethiol, 2-((3-aminopropyl)amino)-, dihydrogen phosphate (ester) hydrate ; Phosphorothioic acid, S-(2-((3-aminopropyl)amino)ethyl) ester, hydrate
Enthalpy of Vaporization: 76.64 kJ/mol
Flash Point: 220.9 °C
Boiling Point: 441.7 °C
Amifostine hydrate (CAS NO.63717-27-1) is used as pharmaceutical intermediate.
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intraperitoneal | 700mg/kg (700mg/kg) | Journal of Medicinal Chemistry. Vol. 12, Pg. 236, 1969. | |
mouse | LD50 | unreported | 375mg/kg (375mg/kg) | Journal of Medicinal Chemistry. Vol. 9, Pg. 911, 1966. |
Poison by unspecified route. Moderately toxic by intraperitoneal route. When heated to decomposition it emits very toxic fumes of NOx, POx, and SOx. See also ESTERS.