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Basic Information
CAS No.: 6385-02-0
Name: MECLOFENAMATE SODIUM
Article Data: 1
Molecular Structure:
Molecular Structure of 6385-02-0 (MECLOFENAMATE SODIUM)
Formula: C14H11 Cl2 N O2 . Na
Molecular Weight: 318.135
Synonyms: Anthranilicacid, N-(2,6-dichloro-m-tolyl)-, monosodium salt (8CI); Benzoic acid,2-[(2,6-dichloro-3-methylphenyl)amino]-, monosodium salt (9CI); CI 583;Meclofenamate sodium; Meclomen; N-(2,6-Dichloro-m-tolyl)anthranilic acid sodiumsalt; Sodium N-(2,6-dichloro-m-tolyl)anthranilate; Sodium meclofenamate; Sodiummeclophenamate
Melting Point: 287-291 °C
Boiling Point: 399.4oC at 760 mmHg
Flash Point: 195.3oC
Solubility: Soluble in water at 50mg/ml. Also soluble in DMF, DMSO or ethanol
Safety: Human systemic effects by ingestion: diarrhea, nausea or vomiting, allergic dermatitis, and fever. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of Cl−, NOx, and Na2O.
PSA: 52.16000
LogP: 3.48190
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Chemistry

IUPAC Name: Sodium 2-(2,6-dichloro-3-methylanilino)benzoate hydrate
Synonyms: 2-((2,6-Dichloro-3-methylphenyl)amino)benzoic Acid Monosodium Salt Monohydrate ; Monosodium N-(2,6-dichloro-m-tolyl)anthranilate monohydrate ;Movens ; N-(2,6-Dichloro-m-tolyl)anthranilic Acid Monosodium Salt Monohydrate ; Sodium meclofenamate ; Sodium meclophenamate
CAS NO: 6385-02-0
Molecular Formula of Sodium meclofenamate (CAS NO.6385-02-0) : C14H12Cl2NNaO3
Molecular Weight of Sodium meclofenamate (CAS NO.6385-02-0) : 336.15
Molecular Structure of Sodium meclofenamate (CAS NO.6385-02-0) :
EINECS: 228-983-3
Mol File: 6385-02-0.mol
Merck : 5779
Flash Point: 195.3 °C
Enthalpy of Vaporization: 68.56 kJ/mol
Boiling Point: 399.4 °C at 760 mmHg
Vapour Pressure: 4.27E-07 mmHg at 25°C
Appearance: colorless crystalline powder,
Solubility: soluble in water

Uses

 Sodium meclofenamate (CAS NO.6385-02-0) has effect on anti-inflammatory, analgesic and antipyretic.

Toxicity Data With Reference

1.    

orl-hmn TDLo:120 mg/kg/6W:GIT,SKN

     ARZNAD    Arzneimittel-Forschung. Drug Research. 33 (1983),631.
2.    

orl-wmn TDLo:3 mg/kg:SKN,MET

     JRHUA9    Journal of Rheumatology. 10 (1983),169.

Safety Profile

Human systemic effects by ingestion: diarrhea, nausea or vomiting, allergic dermatitis, and fever. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of Cl−, NOx, and Na2O.
WGK Germany 3
RTECS CB2975500