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| CAS No.: | 64953-12-4 |
|---|---|
| Name: | Latamoxef sodium |
| Molecular Structure: | |
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| Formula: | C20H18N6Na2O9S |
| Molecular Weight: | 564.48 |
| Synonyms: | 5-Oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[(2R)-carboxy(4-hydroxyphenyl)acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-,disodium salt, (6R,7R)- (9CI);6059S;Antibiotic 6059S;Disodium latamoxef;Festamoxin;LY 12735;LY 127935;Latamoxef sodium;Moxalactam disodium;S 6059;Shiomarin;Shionogi 6059S; |
| EINECS: | 265-288-4 |
| Hazard Symbols: |
 Xn
|
| Risk Codes: | 42/43 |
| Safety: | 22-36/37-45 |
| PSA: | 237.26000 |
| LogP: | -3.46830 |
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- 64963-01-5L-Leucine,L-tyrosyl-D-alanylglycyl-L-phenylalanyl-
- 649662-56-61H-Imidazole,4,5-dichloro-1-[2-nitro-4-(trifluoromethyl)phenyl]-
- 64967-39-1Glycine,N-[3-(2-furanyl)-1-oxo-2-propenyl]-L-phenylalanylglycyl- (9CI)
- 64968-39-4Pyrimidine,1,2,5,6-tetrahydro-4-(4-methoxyphenyl)-2,6-diphenyl-5-(phenylmethylene)-
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Chemistry
Chemical Name: Latamoxef sodium
IUPAC NAME: Disodium 7-[[2-(4-hydroxyphenyl)-3-oxido-3-oxopropanoyl]amino]-7-methoxy-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
CAS No.: 64953-12-4
EINECS: 265-288-4
RTECS: RN6824000
Molecular Formula: C20H18N6Na2O9S
Molecular Weight: 564.44 g/mol
Storage temp.: 2-8°C
Following is the structure of Latamoxef sodium (64953-12-4):
Product Categories about Latamoxef sodium (64953-12-4) are METI - MZForensic and Veterinary Standards;OthersAntibiotics;Penicillins and Cephalosporins (beta-Lactams)More...Close...;Antibacterial;Antibiotics;Antibiotics A to;Antibiotics G-MAntibiotics;Chemical Structure;Chemical Structure Class;Drugs&Metabolites;Interferes with Cell Wall SynthesisSpectrum of Activity;L - ZAlphabetic;M;Mechanism of Action;Neat CompoundsDrugs of Abuse
The chemical synonymous of Latamoxef sodium (64953-12-4) are Moxalactam sodium salt;5-Oxa-1-azabicyclo(4.2.o)oct-2-ene-2-carboxylicacid,7-((carboxy(4-hydroxyphen;6059s;Antibiotic6059-S;Disodiumlatamoxef;Latamoxefsodium;Ly127935;Moxalactamdisodium
Toxicity Data With Reference
| 1. | orl-man TDLo:571 mg/kg/20D-I:GIT | JAMAAP JAMA, Journal of the American Medical Association. 250 (1983),730. | ||
| 2. | ivn-man LDLo:371 mg/kg/17D-I:BLD | DICPBB Drug Intelligence and Clinical Pharmacy. 18 (1984),140. | ||
| 3. | ivn-man TDLo:1143 mg/kg/10D-I:BLD | DICPBB Drug Intelligence and Clinical Pharmacy. 18 (1984),721. | ||
| 4. | ipr-rat LD50:8100 mg/kg | NIIRDN Drugs in Japan. Ethical Drugs, 6th Edition 1982 6 (1982),APP-21. | ||
| 5. | scu-rat LD50:9000 mg/kg | NIIRDN Drugs in Japan. Ethical Drugs, 6th Edition 1982 6 (1982),APP-21. | ||
| 6. | ivn-rat LD50:5500 mg/kg | NIIRDN Drugs in Japan. Ethical Drugs, 6th Edition 1982 6 (1982),APP-21. | ||
| 7. | ipr-mus LD50:8100 mg/kg | NIIRDN Drugs in Japan. Ethical Drugs, 6th Edition 1982 6 (1982),APP-21. | ||
| 8. | scu-mus LD50:9000 mg/kg | NIIRDN Drugs in Japan. Ethical Drugs, 6th Edition 1982 6 (1982),APP-21. | ||
| 9. | ivn-mus LD50:5500 mg/kg | NIIRDN Drugs in Japan. Ethical Drugs, 6th Edition 1982 6 (1982),APP-21. |
Safety Profile
Mildly toxic by several routes. An experimental teratogen. Other experimental reproductive effects. Human systemic effects: ulceration or bleeding from small and large intestine, hemorrhage, thrombocytopenia. When heated to decomposition it emits toxic fumes of SOx, NOx, and Na2O.
Hazard Codes:
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Risk Statements about Latamoxef sodium (64953-12-4):
R42/43: May cause sensitization by inhalation and skin contact.
Safety Statements about Latamoxef sodium (64953-12-4):
S22 Do not breathe dust.
S45 In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S36/37: Wear suitable protective clothing and gloves.