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64953-12-4

Basic Information
CAS No.: 64953-12-4
Name: 5-Oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[(2R)-2-carboxy-2-(4-hydroxyphenyl)acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-,sodium salt (1:2), (6R,7R)-
Molecular Structure:
Molecular Structure of 64953-12-4 (5-Oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[(2R)-2-carboxy-2-(4-hydroxyphenyl)acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-,sodium salt (1:2), (6R,7R)-)
Formula: C20H18N6Na2O9S
Molecular Weight: 564.48
Synonyms: 5-Oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[(2R)-carboxy(4-hydroxyphenyl)acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-,disodium salt, (6R,7R)- (9CI);6059S;Antibiotic 6059S;Disodium latamoxef;Festamoxin;LY 12735;LY 127935;Latamoxef sodium;Moxalactam disodium;S 6059;Shiomarin;Shionogi 6059S;
EINECS: 265-288-4
Density: N/A
Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Solubility: N/A
Appearance: N/A
Hazard Symbols: HarmfulXn
Risk Codes: 42/43
Safety: 22-36/37-45
Transport Information: N/A
PSA: 237.26000
LogP: -3.46830
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Chemistry

Chemical Name: Latamoxef sodium
IUPAC NAME: Disodium 7-[[2-(4-hydroxyphenyl)-3-oxido-3-oxopropanoyl]amino]-7-methoxy-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
CAS No.: 64953-12-4
EINECS: 265-288-4
RTECS: RN6824000
Molecular Formula: C20H18N6Na2O9S
Molecular Weight: 564.44 g/mol
Storage temp.: 2-8°C
Following is the structure of Latamoxef sodium (64953-12-4):


Product Categories about Latamoxef sodium (64953-12-4) are METI - MZForensic and Veterinary Standards;OthersAntibiotics;Penicillins and Cephalosporins (beta-Lactams)More...Close...;Antibacterial;Antibiotics;Antibiotics A to;Antibiotics G-MAntibiotics;Chemical Structure;Chemical Structure Class;Drugs&Metabolites;Interferes with Cell Wall SynthesisSpectrum of Activity;L - ZAlphabetic;M;Mechanism of Action;Neat CompoundsDrugs of Abuse
The chemical synonymous of Latamoxef sodium (64953-12-4) are Moxalactam sodium salt;5-Oxa-1-azabicyclo(4.2.o)oct-2-ene-2-carboxylicacid,7-((carboxy(4-hydroxyphen;6059s;Antibiotic6059-S;Disodiumlatamoxef;Latamoxefsodium;Ly127935;Moxalactamdisodium

Toxicity Data With Reference

1.    

orl-man TDLo:571 mg/kg/20D-I:GIT

    JAMAAP    JAMA, Journal of the American Medical Association. 250 (1983),730.
2.    

ivn-man LDLo:371 mg/kg/17D-I:BLD

    DICPBB    Drug Intelligence and Clinical Pharmacy. 18 (1984),140.
3.    

ivn-man TDLo:1143 mg/kg/10D-I:BLD

    DICPBB    Drug Intelligence and Clinical Pharmacy. 18 (1984),721.
4.    

ipr-rat LD50:8100 mg/kg

    NIIRDN    Drugs in Japan. Ethical Drugs, 6th Edition 1982 6 (1982),APP-21.
5.    

scu-rat LD50:9000 mg/kg

    NIIRDN    Drugs in Japan. Ethical Drugs, 6th Edition 1982 6 (1982),APP-21.
6.    

ivn-rat LD50:5500 mg/kg

    NIIRDN    Drugs in Japan. Ethical Drugs, 6th Edition 1982 6 (1982),APP-21.
7.    

ipr-mus LD50:8100 mg/kg

    NIIRDN    Drugs in Japan. Ethical Drugs, 6th Edition 1982 6 (1982),APP-21.
8.    

scu-mus LD50:9000 mg/kg

    NIIRDN    Drugs in Japan. Ethical Drugs, 6th Edition 1982 6 (1982),APP-21.
9.    

ivn-mus LD50:5500 mg/kg

    NIIRDN    Drugs in Japan. Ethical Drugs, 6th Edition 1982 6 (1982),APP-21.

Safety Profile

Mildly toxic by several routes. An experimental teratogen. Other experimental reproductive effects. Human systemic effects: ulceration or bleeding from small and large intestine, hemorrhage, thrombocytopenia. When heated to decomposition it emits toxic fumes of SOx, NOx, and Na2O.
Hazard Codes:
Xn: Harmful
Risk Statements about Latamoxef sodium (64953-12-4):
R42/43: May cause sensitization by inhalation and skin contact.
Safety Statements about Latamoxef sodium (64953-12-4):
S22 Do not breathe dust.
S45 In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S36/37: Wear suitable protective clothing and gloves.