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CAS No.: | 66176-39-4 |
---|---|
Name: | alpha-Bromo-p-toluenesulphonyl chloride |
Article Data: | 18 |
Molecular Structure: | |
Formula: | C7H6BrClO2S |
Molecular Weight: | 269.546 |
Synonyms: | p-Toluenesulfonylchloride, a-bromo- (6CI,7CI);4-(Bromomethyl)benzene-1-sulfonyl chloride;4-(Bromomethyl)benzenesulfonylchloride;4-(Bromomethyl)phenylsulfonyl chloride;a-Bromo-p-toluenesulfonyl chloride; |
EINECS: | -0 |
Density: | 1.732 g/cm3 |
Melting Point: | 69-76 oC |
Boiling Point: | 329.7 °C at 760 mmHg |
Flash Point: | 153.2 °C |
Appearance: | off-white to light yellow crystalline powder |
Hazard Symbols: | C |
Risk Codes: | 34 |
Safety: | 26-36/37/39-45 |
Transport Information: | UN 3261 |
PSA: | 42.52000 |
LogP: | 3.58980 |
α-bromo-p-toluidine
4-(bromomethyl)benzene-1-sulfonyl chloride
Conditions | Yield |
---|---|
Stage #1: α-bromo-p-toluidine With hydrogenchloride; sodium nitrite In water at -5 - 0℃; Stage #2: With thionyl chloride; copper(l) chloride In water at -5 - 0℃; | 75.9% |
azobisisobutyronitrile
p-toluenesulfonyl chloride
A
4-(bromomethyl)benzene-1-sulfonyl chloride
B
4-(1-bromo-ethyl)-benzenesulfonyl chloride
Conditions | Yield |
---|---|
With N-Bromosuccinimide In 4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran; benzene | A n/a B 66% |
azobisisobutyronitrile
p-toluenesulfonyl chloride
4-(bromomethyl)benzene-1-sulfonyl chloride
Conditions | Yield |
---|---|
With N-Bromosuccinimide In 4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran; benzene | 66% |
With N-Bromosuccinimide In 4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran; benzene | 66% |
p-toluenesulfonyl chloride
4-(bromomethyl)benzene-1-sulfonyl chloride
Conditions | Yield |
---|---|
With N-Bromosuccinimide; dibenzoyl peroxide In tetrachloromethane at 80℃; for 10h; Inert atmosphere; | 65% |
With N-Bromosuccinimide; trityl tetrafluoroborate In dichloromethane at 20℃; Irradiation; Inert atmosphere; chemoselective reaction; | 55% |
With N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile) In benzene for 23h; Reflux; | 36% |
4-bromo-benzaldehyde
phenylmethanethiol
A
4-(bromomethyl)benzene-1-sulfonyl chloride
B
4-(benzylmercapto)benzaldehyde
4-(bromomethyl)benzene-1-sulfonyl chloride
benzylamine
Conditions | Yield |
---|---|
With triethylamine In diethyl ether at 20℃; for 3h; Substitution; | 100% |
With triethylamine In tetrahydrofuran at 0 - 20℃; Inert atmosphere; |
piperidine
4-(bromomethyl)benzene-1-sulfonyl chloride
Conditions | Yield |
---|---|
With triethylamine In diethyl ether at 20℃; for 3h; Substitution; | 100% |
With triethylamine In dichloromethane at 0℃; for 1.25h; Inert atmosphere; | |
With sodium carbonate In water at 20℃; pH=9-10; |
1-indoline
4-(bromomethyl)benzene-1-sulfonyl chloride
Conditions | Yield |
---|---|
With triethylamine In diethyl ether at 20℃; for 3h; Substitution; | 100% |
1,2,3-Benzotriazole
4-(bromomethyl)benzene-1-sulfonyl chloride
Conditions | Yield |
---|---|
With triethylamine In diethyl ether at 20℃; for 3h; Substitution; | 100% |
4-(bromomethyl)benzene-1-sulfonyl chloride
diethylamine
4-(bromomethyl)-N,N-diethylbenzenesulfonamide
Conditions | Yield |
---|---|
With triethylamine In diethyl ether at 20℃; for 3h; Substitution; | 100% |
With N-ethyl-N,N-diisopropylamine In dichloromethane at 0 - 20℃; for 2h; | |
With triethylamine In dichloromethane at 0℃; for 1.25h; Inert atmosphere; | |
With triethylamine In dichloromethane at 0 - 20℃; for 1h; | 0.10 g |