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67227-56-9

Basic Information
CAS No.: 67227-56-9
Name: Fenoldopam
Article Data: 2
Molecular Structure:
Molecular Structure of 67227-56-9 (Fenoldopam)
Formula: C16H16ClNO3
Molecular Weight: 305.761
Synonyms: (?à)-Fenoldopam;(?à)-SKF 82526;Fenoldopam;SKF82526;
EINECS: 266-612-7
Density: 1.38 g/cm3
Boiling Point: 522.6 ºC at 760 mmHg
Flash Point: 269.9 ºC
Solubility: DMSO: >12 mg/mL
Hazard Symbols:
Risk Codes: R22;R36;R42/43   
Safety: S22;S26;S36/37/39
PSA: 72.72000
LogP: 3.06320
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   Fenoldopam (CAS NO.67227-56-9) is a synthetic benzazepine derivative drug that acts as a selective peripheral dopamine D1 receptor weak partial agonist.And it is used as an antihypertensive agent postoperatively, and via IV to treat hypertensive crisis, and also can be called Corlopam ; 6-Chloro-7,8-dihydroxy-1-p-hydroxyphenyl-2,3,4,5-tetrahydro-1H-3-benzazepine ; 1H-3-benzazepine-7,8-diol, 6-chloro-2,3,4,5-tetrahydro-1-(4-hydroxyphenyl)- ;and 6-Chloro-2,3,4,5-tetrahydro-1-(4-hydroxyphenyl)-1H-3-benzazepine-7,8-diol .By activating peripheral D1 receptors, it causes arterial/arteriolar vasodilation leading to a decrease in blood pressure.Adverse effects include flushing, headache, hypotension, reflex tachycardia, angina, and increased intraocular pressure.
  Fenoldopam mesylate (CAS NO.67227-56-9) is irritating to the eyes, so if it is in case of contact with eyes, rinse immediately with plenty of water and seek medical advice; It is may cause sensitization by inhalation and by skin contact, so  people must Wear suitable protective clothing ,suitable gloves and eye/face protection.