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CAS No.: | 67227-56-9 |
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Name: | Fenoldopam |
Article Data: | 2 |
Molecular Structure: | |
Formula: | C16H16ClNO3 |
Molecular Weight: | 305.761 |
Synonyms: | (?à)-Fenoldopam;(?à)-SKF 82526;Fenoldopam;SKF82526; |
EINECS: | 266-612-7 |
Density: | 1.38 g/cm3 |
Boiling Point: | 522.6 ºC at 760 mmHg |
Flash Point: | 269.9 ºC |
Solubility: | DMSO: >12 mg/mL |
Hazard Symbols: | |
Risk Codes: | R22;R36;R42/43 |
Safety: | S22;S26;S36/37/39 |
PSA: | 72.72000 |
LogP: | 3.06320 |
Fenoldopam (CAS NO.67227-56-9) is a synthetic benzazepine derivative drug that acts as a selective peripheral dopamine D1 receptor weak partial agonist.And it is used as an antihypertensive agent postoperatively, and via IV to treat hypertensive crisis, and also can be called Corlopam ; 6-Chloro-7,8-dihydroxy-1-p-hydroxyphenyl-2,3,4,5-tetrahydro-1H-3-benzazepine ; 1H-3-benzazepine-7,8-diol, 6-chloro-2,3,4,5-tetrahydro-1-(4-hydroxyphenyl)- ;and 6-Chloro-2,3,4,5-tetrahydro-1-(4-hydroxyphenyl)-1H-3-benzazepine-7,8-diol .By activating peripheral D1 receptors, it causes arterial/arteriolar vasodilation leading to a decrease in blood pressure.Adverse effects include flushing, headache, hypotension, reflex tachycardia, angina, and increased intraocular pressure.
Fenoldopam mesylate (CAS NO.67227-56-9) is irritating to the eyes, so if it is in case of contact with eyes, rinse immediately with plenty of water and seek medical advice; It is may cause sensitization by inhalation and by skin contact, so people must Wear suitable protective clothing ,suitable gloves and eye/face protection.