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Basic Information
CAS No.: 70-07-5
Name: Mephenoxalone
Article Data: 52
Molecular Structure:
Molecular Structure of 70-07-5 (Mephenoxalone)
Formula: C11H13 N O4
Molecular Weight: 223.229
Synonyms: 2-Oxazolidinone,5-[(o-methoxyphenoxy)methyl]- (6CI,7CI,8CI); (?à)-Mephenoxalone; 5-(o-Methoxyphenoxymethyl)-2-oxazolidinone;5-(o-Methoxyphenoxymethyl)-2-oxazolidone; AHR 233; Control-OM; Dorsiflex;Dorsilon; Ekilan; Lenetran; Lenetran Tab; Lenetranat; Mephenoxalone;Methoxadone; Methoxydon; Methoxydone; Metoxadon; Metoxadone; Moderamin; OM-518;Placidex; Riself; Tranpoise; Trepidone; Valans; Xerene
EINECS: 200-723-3
Density: 1.201g/cm3
Melting Point: 143-145°
Boiling Point: 440°C at 760 mmHg
Flash Point: 219.9°C
Safety: Moderately toxic by ingestion and intraperitoneal routes. A tranquilizer. When heated to decomposition it emits toxic fumes of NOx.
PSA: 56.79000
LogP: 1.51120
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  • 2-Oxazolidinone,5-[(2-methoxyphenoxy)methyl]-

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Chemistry

Product Name: 5-(o-Methoxyphenoxymethyl)-2-oxazolidone (CAS NO.70-07-5)


Molecular Formula: C11H13NO4
Molecular Weight: 223.22g/mol
Mol File: 70-07-5.mol
Einecs: 200-723-3
Boiling point: 440 °C at 760 mmHg
Flash Point: 219.9 °C
Density: 1.201 g/cm3
Surface Tension: 39.2 dyne/cm
Enthalpy of Vaporization: 69.71 kJ/mol
Vapour Pressure: 6.09E-08 mmHg at 25°C
XLogP3-AA: 1.4
H-Bond Donor: 1
H-Bond Acceptor: 4

Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 800mg/kg (800mg/kg)   Revista de la Asociacion Medica Argentina. Vol. 74, Pg. 82, 1960.
mouse LD50 oral > 5gm/kg (5000mg/kg)   Proceedings of the European Society for the Study of Drug Toxicity. Vol. 11, Pg. 212, 1970.
rat LD intraperitoneal > 1gm/kg (1000mg/kg)   Archives Internationales de Pharmacodynamie et de Therapie. Vol. 134, Pg. 198, 1961.
rat LD50 oral 3820mg/kg (3820mg/kg) SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE

BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION		 Toxicology and Applied Pharmacology. Vol. 6, Pg. 642, 1964.

Safety Profile

Moderately toxic by ingestion and intraperitoneal routes. A tranquilizer. When heated to decomposition it emits toxic fumes of NOx.

Specification

 5-(o-Methoxyphenoxymethyl)-2-oxazolidone ,its CAS NO. is 70-07-5,the synonyms is Mephenoxalone ; 5-[(2-Methoxyphenoxy)methyl]-2-oxazolidinone .