Products Categories
| CAS No.: | 71-23-8 |
|---|---|
| Name: | 1-Propanol |
| Molecular Structure: | |
|
|
|
| Formula: | C3H8O |
| Molecular Weight: | 60.0959 |
| Synonyms: | Propylalcohol (8CI);1-Hydroxypropane;Ethylcarbinol;NSC 30300;Optal;Osmosolextra;Propanol;n-Propanol;n-Propyl alcohol; |
| EINECS: | 200-746-9 |
| Density: | 0.795 g/cm3 |
| Melting Point: | -127 °C |
| Boiling Point: | 95.784 °C at 760 mmHg |
| Flash Point: | 15 °C |
| Solubility: | soluble in water |
| Appearance: | colourless liquid |
| Hazard Symbols: |
 F,  Xi
|
| Risk Codes: | 11-41-67 |
| Safety: | 7-16-24-26-39 |
| Transport Information: | UN 1274 3/PG 2 |
| PSA: | 20.23000 |
| LogP: | 0.38870 |
- 81281-59-67-Benzylideneaminotheophylline
- 82993-81-5D-threo-Ritalinic acid hydrochloride
- 73441-42-6METHYL-5-CHLORO-2,2-DIMETHYLVALERATE
- 852475-26-4MC1568
- 958254-66-51H-Imidazo[4,5-b]pyridine-2-carboxaldehyde, 1-methyl-, hydrochloride
- 99170-93-1N-Methyl-2-oxazolamine
- 717878-06-31-(4-fluorophenyl)-4-nitro-1H-imidazole
- 914458-26-7[5-(2-fluorophenyl)-1-pentyl-1H-pyrrol-3-yl]-1-naphthalenyl-Methanone
- 894852-01-87-BROMO-2,2-DIMETHYL-2H-PYRIDO[3,2-B][1,4]OXAZIN-3(4H)-ONE
- 71825-51-92-methyl-2-(4-nitrophenyl)propanenitrile
| Conditions | Yield |
|---|---|
| With hydrogen; mer-Os(PPh3)3HBr(CO) at 150℃; under 22800 Torr; for 1.66667h; Product distribution; | 100% |
| With hydrogen; mer-Os(PPh3)3HBr(CO) In toluene at 150℃; under 22800 Torr; for 1.7h; | 100% |
| With hydrogen In water at 60℃; under 15001.5 Torr; for 8h; Reagent/catalyst; Autoclave; | 100% |
| Conditions | Yield |
|---|---|
| With hydrogen; poly-1,2,3-triazolyl ferrocenyl dendrimer-Pd nanoparticle In methanol; chloroform at 25℃; under 760.051 Torr; | 100% |
| With (1+)*OTf(1-); Gantrez 149; bis[(2-diphenylphosphino)ethyl]amine hydrochloride; hydrogen at 25℃; Mechanism; Product distribution; 1.) CH3CN, 10 h; 2.) H2O; var. Rh(I) complex cat., solvent; | 95% |
| With <(Pd5Phen2)OAc>n; hydrogen In water at 30℃; Product distribution; hydogen and substrate concentration dependence; | 90% |
| Conditions | Yield |
|---|---|
| With C61H62ClN3P2Ru In dichloromethane-d2 at 50℃; under 3040.2 Torr; for 10h; Reagent/catalyst; Time; | 100% |
- 624-48-6
dimethyl cis-but-2-ene-1,4-dioate
A
- 109-99-9
tetrahydrofuran
B
- 13436-45-8
2-methoxytetrahydrofuran
C
- 96-48-0
4-butanolide
D
- 71-23-8
propan-1-ol
E
- 64001-06-5
2-(4'-hydroxybutoxy)-tetrahydrofuran
F
- 110-63-4
Butane-1,4-diol
G
- 71-36-3
butan-1-ol
| Conditions | Yield |
|---|---|
| With hydrogen; copper catalyst, T 4489, Sud-Chemie AG, Munich at 150 - 280℃; under 187519 Torr; Neat liquid(s) and gas(es)/vapour(s); | A 1% B n/a C 0.4% D n/a E n/a F 98% G 0.5% |
| Conditions | Yield |
|---|---|
| With hydrogen In water at 119.84℃; under 60006 Torr; for 2h; Catalytic behavior; Reagent/catalyst; Autoclave; Sealed tube; | 97% |
- 802294-64-0
propionic acid
- 71-23-8
propan-1-ol
| Conditions | Yield |
|---|---|
| Stage #1: propionic acid With borane-2-methyltetrahydrofuran complex In 2-methyltetrahydrofuran at 0 - 20℃; for 2h; Stage #2: With water In 2-methyltetrahydrofuran Product distribution / selectivity; | 96.5% |
| With hydrogen In water at 119.84℃; under 7500.75 - 60006 Torr; for 2h; Catalytic behavior; Reagent/catalyst; Autoclave; Sealed tube; | 96% |
| With hydrogen In water at 100℃; under 37503.8 Torr; for 12h; Pressure; Reagent/catalyst; Autoclave; | 94% |
| Conditions | Yield |
|---|---|
| With [C6H3-2,6-(OP(tBu)2)2]IrH2; trifluorormethanesulfonic acid; water; hydrogen In 1,4-dioxane at 125℃; under 5171.62 Torr; Temperature; Pressure; Solvent; Autoclave; | 95% |
| With hydrogen In water at 210℃; under 30753.1 Torr; for 5h; Autoclave; Sealed tube; | |
| With hydrogen In water at 179.84℃; under 37503.8 Torr; for 12h; | 80 %Chromat. |
| at 315℃; Gas phase; |
- 71-23-8
propan-1-ol
| Conditions | Yield |
|---|---|
| With N-ethyl-N-hydroxy-ethanamine; sodium hydroxide In tert-butyl alcohol for 2h; | 93% |
- 53720-59-5
dipropyl phenylarsonate
- 100-39-0
benzyl bromide
A
- 71-23-8
propan-1-ol
B
- 106-94-5
propyl bromide
C
- 75099-95-5
C16H19AsO3
| Conditions | Yield |
|---|---|
| at 150℃; for 1.5h; | A n/a B n/a C 91.7% |
| Conditions | Yield |
|---|---|
| With hydrogen at 180℃; under 37503.8 Torr; Catalytic behavior; chemoselective reaction; | A 91.2% B 7.8% |
| With hydrogen In water at 179.84℃; under 22502.3 Torr; for 10h; Autoclave; | A 76% B 9% |
| With hydrogen In water at 130℃; under 30003 Torr; for 24h; |
- 105-60-22H-Azepin-2-one,hexahydro-
- 125-71-3Morphinan,3-methoxy-17-methyl-, (9α,13α,14α)-
- 5949-29-1Citric acid monohydrate
- 9004-64-2Hydroxypropyl cellulose
- 7719-09-7Thionyl chloride
- 102-71-6Ethanol,2,2',2''-nitrilotris-
- 8061-52-7Calcium lignosulfonate
- 3055-99-03,6,9,12,15,18,21,24,27-Nonaoxanonatriacontan-1-ol
- 104987-11-3Tacrolimus
- 141-53-7Sodium formate
- 8001-54-5Quaternary ammonium compounds, alkylbenzyldimethyl, chlorides
- 9003-39-8Povidone
- 10161-34-9Trenbolone acetate
- 402957-28-2Telaprevir
- 68-19-9Cyanocobalamin
- Total:29 Page 1 of 1 1
What can I do for you?
Get Best Price
Specification
The 1-Propanol, with the CAS registry number 71-23-8,is also known as Propan-1-ol; Propyl alcohol. It belongs to the product categories of Carbon Steel Flex-Spout Cans;Semi-Bulk Solvents.Its EINECS number is 200-746-9. This chemical's molecular formula is C3H8O and molecular weight is 60.10. What's more,Its systematic name is 1-Propanol.It is a colorless liquid made by oxidation of aliphatic hydrocarbons that is used as a solvent and chemical intermediate.It may form peroxides in contact with air.And it is incompatible with alkali metals, alkaline earths, aluminium, oxidizing agents, nitro compounds,highly flammable.And it is used as a solvent in the pharmaceutical industry, and for resins and cellulose esters.
Physical properties about 1-Propanol are:
(1)ACD/LogP: 0.329; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 0.33; (4)ACD/LogD (pH 7.4): 0.33; (5)ACD/BCF (pH 5.5): 1.05; (6)ACD/BCF (pH 7.4): 1.05; (7)ACD/KOC (pH 5.5): 35.97; (8)ACD/KOC (pH 7.4): 35.97; (9)#H bond acceptors: 1; (10)#H bond donors: 1; (11)#Freely Rotating Bonds: 2; (12)Index of Refraction: 1.38; (13)Molar Refractivity: 17.482 cm3; (14)Molar Volume: 75.562 cm3; (15)Surface Tension: 24.576000213623 dyne/cm; (16)Density: 0.795 g/cm3; (17)Flash Point: 15 °C; (18)Enthalpy of Vaporization: 41.44 kJ/mol; (19)Boiling Point: 95.784 °C at 760 mmHg; (20)Vapour Pressure: 26.3169994354248 mmHg at 25°C.
You can still convert the following datas into molecular structure:
(1)SMILES:CCCO;
(2)Std. InChI:InChI=1S/C3H8O/c1-2-3-4/h4H,2-3H2,1H3;
(3)Std. InChIKey:BDERNNFJNOPAEC-UHFFFAOYSA-N.
Preparation of 1-Propanol:
It is a major constituent of fusel oil, a by-product formed from certain amino acids when potatoes or grains are fermented to produce ethanol.
It is manufactured by catalytic hydrogenation of propionaldehyde. The propionaldehyde is itself produced via the oxo process, by hydroformylation of ethylene using carbon monoxide and hydrogen in the presence of a catalyst such as cobalt octacarbonyl or a rhodium complex.
H2C=CH2 + CO + H2 → CH3CH2CH=O
CH3CH2CH=O + H2 → CH3CH2CH2OH
A traditional laboratory preparation of 1-propanol involves treating n-propyl iodide with moist Ag2O.
Safety Information of 1-Propanol:
The 1-Propanol is extremely irritating when contact with eyes and may cause burns.The vapors irritate nose and throat. In high concentrations, it may cause nausea, dizziness, headache, and stupor.So we should keep container tightly closed and away from heat. When you use it ,wear eye/face protection and avoid contact with skin. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
The toxicity data of 1-Propanol as follows:
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| cat | LDLo | intravenous | 4008mg/kg (4008mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 16, Pg. 1, 1920. | |
| dog | LDLo | oral | 3gm/kg (3000mg/kg) | BLOOD: HEMORRHAGE GASTROINTESTINAL: OTHER CHANGES | Comptes Rendus Hebdomadaires des Seances, Academie des Sciences. Vol. 81, Pg. 192, 1875. |
| dog | LDLo | subcutaneous | 4gm/kg (4000mg/kg) | BLOOD: HEMORRHAGE GASTROINTESTINAL: OTHER CHANGES | Comptes Rendus Hebdomadaires des Seances, Academie des Sciences. Vol. 81, Pg. 192, 1875. |
| guinea pig | LD50 | intraperitoneal | 1208mg/kg (1208mg/kg) | EHP, Environmental Health Perspectives. Vol. 61, Pg. 321, 1985. | |
| hamster | LD50 | intraperitoneal | 2338mg/kg (2338mg/kg) | EHP, Environmental Health Perspectives. Vol. 61, Pg. 321, 1985. | |
| mammal (species unspecified) | LDLo | subcutaneous | 5gm/kg (5000mg/kg) | LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE BEHAVIORAL: GENERAL ANESTHETIC | Archiv fuer Toxikologie. Vol. 16, Pg. 84, 1956. |
| mouse | LC50 | inhalation | 48gm/m3 (48000mg/m3) | Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 18(3), Pg. 48, 1974. | |
| mouse | LD50 | intraperitoneal | 3125mg/kg (3125mg/kg) | EHP, Environmental Health Perspectives. Vol. 61, Pg. 321, 1985. | |
| mouse | LD50 | intravenous | 697mg/kg (697mg/kg) | EHP, Environmental Health Perspectives. Vol. 61, Pg. 321, 1985. | |
| mouse | LD50 | oral | 6800mg/kg (6800mg/kg) | Proceedings of the European Society for the Study of Drug Toxicity. Vol. 9, Pg. 276, 1968. | |
| mouse | LD50 | subcutaneous | 4700mg/kg (4700mg/kg) | Toxicology and Applied Pharmacology. Vol. 18, Pg. 185, 1971. | |
| rabbit | LD50 | intraperitoneal | 515mg/kg (515mg/kg) | EHP, Environmental Health Perspectives. Vol. 61, Pg. 321, 1985. | |
| rabbit | LD50 | intravenous | 483mg/kg (483mg/kg) | EHP, Environmental Health Perspectives. Vol. 61, Pg. 321, 1985. | |
| rabbit | LD50 | oral | 2825mg/kg (2825mg/kg) | Industrial Medicine and Surgery. Vol. 41, Pg. 31, 1972. | |
| rabbit | LD50 | skin | 5040mg/kg (5040mg/kg) | AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 10, Pg. 61, 1954. | |
| rabbit | LDLo | subcutaneous | 3gm/kg (3000mg/kg) | "Zur Pharmakologie Ungesattigter Alkohole, Dissertation," Bock, H., Pharmakologischen Institu der Universitat Breslau, Poland, 1930Vol. -, Pg. -, 1930. | |
| rabbit | LDLo | unreported | 4500mg/kg (4500mg/kg) | Therapeutische Monatshefte. Vol. 6, Pg. 327, 1892. | |
| rat | LCLo | inhalation | 4000ppm/4H (4000ppm) | AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 10, Pg. 61, 1954. | |
| rat | LD50 | intraperitoneal | 2164mg/kg (2164mg/kg) | EHP, Environmental Health Perspectives. Vol. 61, Pg. 321, 1985. | |
| rat | LD50 | intravenous | 590mg/kg (590mg/kg) | EHP, Environmental Health Perspectives. Vol. 61, Pg. 321, 1985. | |
| rat | LD50 | oral | 1870mg/kg (1870mg/kg) | AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 10, Pg. 61, 1954. | |
| women | LDLo | oral | 5700mg/kg (5700mg/kg) | LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES CARDIAC: OTHER CHANGES | Archiv fuer Toxikologie. Vol. 16, Pg. 84, 1956. |