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| CAS No.: | 71447-49-9 |
|---|---|
| Name: | Gonadorelin acetate |
| Molecular Structure: | |
 |
|
| Formula: | C55H75N17O13.2(C2H4O2) |
| Molecular Weight: | 1302.59 |
| Synonyms: | Glp-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2;Luteinizing hormone-releasing hormone, diacetate (salt);Gonadorelllin Acetate;LHRH diacetate; |
| EINECS: | 232-895-0 |
| Solubility: | H2O: 25 mg/mL, clear, faintly yellow |
| Appearance: | powder |
| Hazard Symbols: |
 T
|
| Risk Codes: | 60 |
| Safety: | 53-45 |
| PSA: | 546.73000 |
| LogP: | 1.28920 |
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Specification
The Gonadorelin diacetate is an organic compound with the formula C55H75N17O13.2(C2H4O2). The systematic name of this chemical is Luteinizing hormone-releasing hormone, diacetate (salt). With the CAS registry number 71447-49-9, it is also named as LHRH diacetate. The product's categories are Amino Acid Derivatives; Peptide. It is powder which should be stored at the temperature of -20 °C. Besides, when heated to decomposition it emits toxic fumes of NOx.
When you are using this chemical, please be cautious about it as the following:
It may impair fertility. In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) Gonadorelin diacetate should be avoided exposure - obtain special instructions before use.
The following are the toxicity data which has been tested.
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intravenous | 303mg/kg (303mg/kg) | Drugs in Japan Vol. 6, Pg. 273, 1982. | |
| mouse | LD50 | intravenous | 416mg/kg (416mg/kg) | Drugs in Japan Vol. -, Pg. 474, 1995. | |
| mouse | LD50 | oral | > 4gm/kg (4000mg/kg) | Drugs in Japan Vol. -, Pg. 474, 1995. | |
| mouse | LD50 | subcutaneous | > 2gm/kg (2000mg/kg) | Drugs in Japan Vol. 6, Pg. 273, 1982. | |
| rat | LD50 | intravenous | 154mg/kg (154mg/kg) | Drugs in Japan Vol. 6, Pg. 273, 1982. | |
| rat | LD50 | intravenous | 203mg/kg (203mg/kg) | Drugs in Japan Vol. -, Pg. 474, 1995. | |
| rat | LD50 | oral | > 3gm/kg (3000mg/kg) | Drugs in Japan Vol. -, Pg. 474, 1995. | |
| rat | LD50 | subcutaneous | > 2gm/kg (2000mg/kg) | Drugs in Japan Vol. 6, Pg. 273, 1982. |