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Basic Information
| CAS No.: | 71771-90-9 |
|---|---|
| Name: | R(-)-DENOPAMINE |
| Article Data: | 12 |
| Molecular Structure: | |
|
|
|
| Formula: | C18H23 N O4 |
| Molecular Weight: | 317.385 |
| Synonyms: | Benzenemethanol,a-[[[2-(3,4-dimethoxyphenyl)ethyl]amino]methyl]-4-hydroxy-,(R)-; (-)-Denopamine; (R)-(-)-Denopamine; Carguto; Denopamine; Kalgut; TA 064 |
| Density: | 1.177g/cm3 |
| Melting Point: | 135°C |
| Boiling Point: | 518.8°C at 760 mmHg |
| Flash Point: | 267.6°C |
| Solubility: | DMSO: 26 mg/mL, soluble |
| Hazard Symbols: |
 Xn
|
| Risk Codes: | 62-63 |
| Safety: | Moderately toxic by intraperitoneal route. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx. |
| PSA: | 70.95000 |
| LogP: | 2.66600 |
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- Total:24 Page 1 of 1 1
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R(-)-DENOPAMINE
Chemistry
Formula C18H23NO4
Mol. mass 317.37 g/mol
form: powder
color: white
storage temp.: 2-8°C
solubility DMSO: 26 mg/mL, soluble
Mol. mass 317.37 g/mol
form: powder
color: white
storage temp.: 2-8°C
solubility DMSO: 26 mg/mL, soluble
Uses
Denopamine is a cardiotonic drug which can be used in the treatment of angina.
Denopamine may also have potential uses in the treatment of congestive heart failure and for clearing pulmonary oedema.
Denopamine may also have potential uses in the treatment of congestive heart failure and for clearing pulmonary oedema.
Toxicity Data With Reference
| 1. | orl-rat LD50:9369 mg/kg | OYYAA2 Oyo Yakuri. Pharmacometrics. 32 (1986),751. | ||
| 2. | ipr-rat LD50:1785 mg/kg | OYYAA2 Oyo Yakuri. Pharmacometrics. 32 (1986),751. |
Safety Profile
Moderately toxic by intraperitoneal route. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx.