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72822-12-9

Basic Information
CAS No.: 72822-12-9
Name: Dapiprazole
Article Data: 4
Molecular Structure:
Molecular Structure of 72822-12-9 (Dapiprazole)
Formula: C19H27 N5
Molecular Weight: 325.457
Synonyms: Dapiprazole
Density: 1.22 g/cm3
Melting Point: 158-160°
Boiling Point: 538.9 ºC at 760 mmHg
Flash Point: 279.7 ºC
PSA: 37.19000
LogP: 2.29040
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Chemistry

Molecular Structure:

Molecular Formula: C19H27N5
Molecular Weight: 325.4512
IUPAC Name: 3-[2-[4-(2-Methylphenyl)piperazin-1-yl]ethyl]-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyridine
Synonyms of Dapiprazole (CAS NO.72822-12-9): 5,6,7,8-Tetrahydro-3-(2-(4-(o-tolyl)-1-piperazinyl)ethyl)-s-triazolo(4,3-a)pyridine ; Dapiprazol ; Dapiprazol [German] ; Dapirazol ; Dapirazol [INN-Spanish] ; Dapirazolum ; Dapirazolum [INN-Latin] ; Glamidolo ; Remydrial ; Reversil ; UNII-5RNZ8GJO7K ; UNII-DS9UJN1I0X ; 1,2,4-Triazolo(4,3-a)pyridine, 5,6,7,8-tetrahydro-3-(2-(4-(2-methylphenyl)-1-piperazinyl)ethyl)-
CAS NO: 72822-12-9
Classification Code: Adrenergic Agents ; Adrenergic Antagonists ; Adrenergic alpha-antagonists ; Antipsychotic agents ; Central Nervous System Agents ; Central Nervous System Depressants ; Drug / Therapeutic Agent ; Neurotransmitter Agents ; Psychotropic Drugs ; Tranquilizing Agents
Index of Refraction: 1.658
Molar Refractivity: 97.7 cm3
Molar Volume: 265.2 cm3
Surface Tension: 49.3 dyne/cm
Density: 1.22 g/cm3
Flash Point: 279.7 °C
Enthalpy of Vaporization: 81.62 kJ/mol
Boiling Point: 538.9 °C at 760 mmHg
Vapour Pressureof Dapiprazole (CAS NO.72822-12-9): 1.11E-11 mmHg at 25°C

Uses

  Dapiprazole (CAS NO.72822-12-9) is used to reverse mydriasis after eye examination.

Toxicity Data With Reference


Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 260mg/kg (260mg/kg) SENSE ORGANS AND SPECIAL SENSES: MIOSIS (PUPILLARY CONSTRICTION): EYE

BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)

BEHAVIORAL: ATAXIA
Arzneimittel-Forschung. Drug Research. Vol. 32, Pg. 668, 1982.