Products Categories
CAS No.: | 73305-09-6 |
---|---|
Name: | 5-METHOXY-2,3-DIHYDRO-1H-INDEN-2-AMINE |
Article Data: | 12 |
Molecular Structure: | |
Formula: | C10H13 N O |
Molecular Weight: | 163.219 |
Synonyms: | 2-Amino-5-methoxyindan;5-Methoxy-2,3-dihydro-1H-inden-2-amine; 5-Methoxy-2-indanamine;5-Methoxyindan-2-ylamine |
Density: | 1.087±0.06 g/cm3(Predicted) |
Boiling Point: | 277.6±40.0 °C(Predicted) |
PSA: | 35.25000 |
LogP: | 1.82140 |
5-(methyloxy)-2,3-dihydro-1H-inden-2-amine hydrochloride
(±)-2-amino-5-methoxyindane
Conditions | Yield |
---|---|
With sodium hydroxide In methanol; water at 0 - 25℃; for 3h; | 95% |
5-methoxy-indan-1,2-dione 2-oxime
(±)-2-amino-5-methoxyindane
Conditions | Yield |
---|---|
Stage #1: 5-methoxy-indan-1,2-dione 2-oxime With sulfuric acid; hydrogen; palladium 10% on activated carbon In acetic acid under 3102.97 Torr; for 18h; Stage #2: With sodium hydroxide In water at 0℃; pH=10; | 37% |
Stage #1: 5-methoxy-indan-1,2-dione 2-oxime With sulfuric acid; hydrogen; palladium 10% on activated carbon In acetic acid under 3102.97 Torr; for 18h; Stage #2: With sodium hydroxide In water at 0℃; pH=10; | 37% |
With sulfuric acid; hydrogen; acetic acid; palladium on activated charcoal under 3102.97 Torr; for 18h; | 33% |
2-(hydroxyimino)-6-methoxy-2,3-dihydro-1H-inden-1-one
(±)-2-amino-5-methoxyindane
Conditions | Yield |
---|---|
With sulfuric acid; palladium-carbon; palladium(II) chloride In acetic acid | |
With sulfuric acid; palladium-carbon; palladium(II) chloride In acetic acid | |
With sulfuric acid; palladium; acetic acid Hydrogenation; |
2-amino-6-methoxy-indan-1-ol; hydrochloride
(±)-2-amino-5-methoxyindane
Conditions | Yield |
---|---|
With sulfuric acid; palladium; acetic acid Hydrogenation; |
5-methoxy-1-indanone
(±)-2-amino-5-methoxyindane
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 85 percent / n-butylnitrite; conc. aq. HCl / methanol / 0.5 h / 40 °C 2: H2; H2SO4 / 10percent Pd/C / acetic acid / 7 h / 2585.81 Torr View Scheme | |
Multi-step reaction with 2 steps 1: 85 percent / n-butylnitrite; conc. aq. HCl / methanol / 0.5 h / 40 °C 2: H2; H2SO4 / 10 percent Pd/C / acetic acid / 7 h / 2585.74 Torr View Scheme | |
Multi-step reaction with 4 steps 1: bromine / ethyl acetate / 0.5 h / 10 - 20 °C 2: N,N-dimethyl-formamide / 2 h / 20 °C 3: hydrazine hydrate / methanol / 6 h / Reflux 4: potassium hydroxide / diethylene glycol dimethyl ether / 2 h / 120 °C View Scheme | |
Multi-step reaction with 2 steps 1: hydrogenchloride / methanol / 2 h / 45 °C 2: sulfuric acid; acetic acid; palladium on activated charcoal; hydrogen / 12 h / 25 °C / 775.74 Torr View Scheme |
2-bromo-5-methoxyindan-1-one
(±)-2-amino-5-methoxyindane
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: N,N-dimethyl-formamide / 2 h / 20 °C 2: hydrazine hydrate / methanol / 6 h / Reflux 3: potassium hydroxide / diethylene glycol dimethyl ether / 2 h / 120 °C View Scheme |
(±)-2-amino-5-methoxyindane
Conditions | Yield |
---|---|
With potassium hydroxide In diethylene glycol dimethyl ether at 120℃; for 2h; | 73.44g |
(±)-2-amino-5-methoxyindane
Conditions | Yield |
---|---|
With sulfuric acid; palladium on activated charcoal; hydrogen; acetic acid at 25℃; under 775.743 Torr; for 12h; |
phthalic anhydride
(±)-2-amino-5-methoxyindane
2-(5-methoxyindane-2-yl)isoindole-1,3,dione
Conditions | Yield |
---|---|
With sodium hydride In N,N-dimethyl-formamide at 125℃; for 96h; | 68% |
2-vinylpyridine
(±)-2-amino-5-methoxyindane
Conditions | Yield |
---|---|
With acetic acid In methanol Heating; | 30% |