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| CAS No.: | 7385-67-3 |
|---|---|
| Name: | NILE RED |
| Article Data: | 11 |
| Molecular Structure: | |
|
|
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| Formula: | C20H18 N2 O2 |
| Molecular Weight: | 318.375 |
| Synonyms: | 9-(Diethylamino)-5H-benzo[a]phenoxazin-5-one;A 84655; Nile Blue A oxazone; Nile red; Phenoxazone 9 |
| EINECS: | 230-966-0 |
| Density: | 1.23g/cm3 |
| Melting Point: |
203-205 °C(lit.) |
| Boiling Point: | 484.7°C at 760 mmHg |
| Flash Point: | 246.9°C |
| Solubility: | Toxicity data (The meaning of any abbre">
Stability
Toxicology
Toxicity data |
| Appearance: | solid |
| Safety: | 279110 |
| PSA: | 46.34000 |
| LogP: | 4.29220 |
- 81281-59-67-Benzylideneaminotheophylline
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- 958254-66-51H-Imidazo[4,5-b]pyridine-2-carboxaldehyde, 1-methyl-, hydrochloride
- 99170-93-1N-Methyl-2-oxazolamine
- 914458-26-7[5-(2-fluorophenyl)-1-pentyl-1H-pyrrol-3-yl]-1-naphthalenyl-Methanone
- 894852-01-87-BROMO-2,2-DIMETHYL-2H-PYRIDO[3,2-B][1,4]OXAZIN-3(4H)-ONE
- 90221-55-92-bromo-5-methylbenzaldehyde
- 885590-99-82,3-DIFLUORO-4-IODOBENZALDEHYDE
- 97730-31-9(S)-4'-(2-Methylbutyl)Biphenyl-4-Carbonitrile
| Conditions | Yield |
|---|---|
| In toluene at 120℃; for 12h; Inert atmosphere; | 79.1% |
| In N,N-dimethyl-formamide at 150℃; for 4h; Inert atmosphere; | 21% |
- 7385-67-3
Nile Red
| Conditions | Yield |
|---|---|
| With L-Cysteine In dimethyl sulfoxide at 20℃; for 0.166667h; pH=7.4; Reagent/catalyst; |
| Conditions | Yield |
|---|---|
| In N,N-dimethyl-formamide at 80℃; for 16h; | 80% |
| Conditions | Yield |
|---|---|
| Stage #1: 3-diethylaminophenol With hydrogenchloride; sodium nitrite In water at 0 - 5℃; for 4h; Stage #2: α-naphthol In N,N-dimethyl-formamide at 70℃; for 8h; | 505 mg |
| Stage #1: 3-diethylaminophenol With hydrogenchloride; sodium nitrite In ethanol; water at 0 - 5℃; for 4h; Stage #2: α-naphthol In ethanol; water; N,N-dimethyl-formamide at 80℃; for 4h; |
| Conditions | Yield |
|---|---|
| Multi-step reaction with 2 steps 1: sodium nitrite; hydrogenchloride / 4 h / 0 °C 2: toluene / 12 h / 120 °C / Inert atmosphere View Scheme | |
| Multi-step reaction with 2 steps 1: sodium nitrite; hydrogenchloride / water / 1.5 h / 0 °C 2: N,N-dimethyl-formamide / 4 h / 150 °C / Inert atmosphere View Scheme |
| Conditions | Yield |
|---|---|
| In N,N-dimethyl-formamide at 150℃; | 15% |
| Conditions | Yield |
|---|---|
| In N,N-dimethyl-formamide for 4h; Reflux; | 24% |
| Conditions | Yield |
|---|---|
| With L-Cysteine |
- 7385-67-3
Nile Red
| Conditions | Yield |
|---|---|
| With sulfuric acid; xylene |
- 7385-67-3
Nile Red
| Conditions | Yield |
|---|---|
| With hydrogenchloride; xylene |
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Chemistry
Molecular Structure:
Molecular Formula: C20H18N2O2
Molecular Weight: 318.3691
IUPAC Name: 9-(Diethylamino)benzo[a]phenoxazin-5-one
Synonyms of Nile red (CAS NO.7385-67-3): 9-(Diethylamino)-5H-benzo(a)phenoxazin-5-one ; EINECS 230-966-0 ; 5H-Benzo(a)phenoxazin-5-one, 9-(diethylamino)- ; 9-(Diethylamino)benzo(a)phenoxazin-5(5H)-one
CAS NO: 7385-67-3
Classification Code: Coloring Agents ; Fluorescent dyes ; Indicators and Reagents ; Luminescent Agents
Melting point: 203-205 °C
Index of Refraction: 1.643
Molar Refractivity: 93.4 cm3
Molar Volume: 257.9 cm3
Surface Tension: 45.7 dyne/cm
Density: 1.23 g/cm3
Flash Point: 246.9 °C
Enthalpy of Vaporization: 75.01 kJ/mol
Boiling Point: 484.7 °C at 760 mmHg
Vapour Pressure of Nile red (CAS NO.7385-67-3): 1.5E-09 mmHg at 25°C
Safety Profile
Safety Statements of Nile red (CAS NO.7385-67-3): 24/25
S24/25: Avoid contact with skin and eyes.
WGK Germany: 3
F: 8-10