CAS No.7444-29-3,5,10-Methenyltetrahydrofolic acid Suppliers

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Basic Information

Molecular Structure:
CAS No.:	7444-29-3
Name:	5,10-Methenyltetrahydrofolic acid

Formula:	C₂₀H₂₃N₇O₇
Molecular Weight:	473.44
Synonyms:	5,10-Methylene-THF;5,10-methenyl-THF;5,10-methylenetetrahydrofolate(2-);Anhydroleucovorin A;n5-n10-CH-THF;3-Amino-8-[p-[(1,3-dicarboxypropyl)carbamoyl]phenyl]-1,2,5,6,6a,7-hexahydro-1-oxo-8H-imidazo[1,5-f]pteridin-10-ium hydroxide, inner salt (7CI);Imidazo[1,5-f]pteridinium, 3-amino-8-[4-[[[(1S)-1,3-dicarboxypropyl]amino]carbonyl]phenyl]-1,2,5,6,6a,7-hexahydro-1-oxo-, inner salt, (6aR)- (9CI);n5-n10-methenyltetrahydrofolate;1H-Imidazo[1,5-f]pteridin-10-ium, 3-amino-8-[p-[(1,3-dicarboxypropyl)carbamoyl]phenyl]-2,5,6,6a,7,8-hexahydro-1-oxo-, hydroxide, inner salt (8CI);Methenyltetrahydrofolic acid;(6R)-5,10-CH2-H4folate;Leucovorin, anhydro-;3-Amino-8-[p-[(L-1,3-dicarboxypropyl)carbamoyl]phenyl]-1,2,5,6,6a,7-hexahydro-1-oxo-8H-imidazo[1,5-f]pteridin-10-ium hydroxide, inner salt (6CI);methenyl-THF;L-glutamic acid, N-[4-[(6aR)-3-amino-1,4,5,6,6a,7-hexahydro-1-oxoimidazo[1,5-f]pteridinium-8-yl]benzoyl]-, inner salt;Leucovorin A, anhydro-;5,10-methylenetetrahydrofolate;methenyl-tetrahydrofolate;5,10-Methenyltetrahydropteroylglutamate;5,10-methenyltetrahydrofolate;Anhydro leucovorin, 5,10-methenyltetrahydrofolate;Anhydro leucovorin,;Imidazo[1,5-f]pteridinium,3-amino-8-[4- [[[(1S)-1,3-dicarboxypropyl]amino]carbonyl]- phenyl]-1,2,5,6,6a,7-hexahydro-1-oxo-,inner salt,(6aR)-;CH-THF;anhydroleucovorin;N-(5,10-methylene-5,6,7,8-tetrahydropteroyl)-L-glutamate;N-{4-[(6aR)-3-amino-1-oxo-1,2,5,6,6a,7-hexahydroimidazo[1,5-f]pteridin-8(9H)-yl]benzoyl}-L-glutamate;Imidazo[1,5-f]pteridinium, 3-amino-8-[4-[[(1,3-dicarboxypropyl)amino]carbonyl]phenyl]-1,2,5,6,6a,7-hexahydro-1-oxo-, inner salt, [R-(R,S)]-;methenyl-H4F;
PSA:	193.75000
LogP:	0.52040

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Specification

5,10-Methenyltetrahydrofolate (5,10-CH=THF) is a form of tetrahydrofolate that is an intermediate in metabolism. 5,10-CH=THF is a coenzyme that accepts and donates methenyl (CH=) groups.
It is produced from 5,10-methylenetetrahydrofolate by either a NAD+ dependent methylenetetrahydrofolate dehydrogenase, or a NADP+ dependent dehydrogense. It can also be produced as an intermediate in histidine catabolism, by formiminotransferase cyclodeaminase, from 5-formiminotetrahydrofolate.
5,10-CH=THF is a substrate for methenyltetrahydrofolate cyclohydrolase, which converts it into 10-formyltetrahydrofolate.