Products Categories
CAS No.: | 74847-35-1 |
---|---|
Name: | Pyronaridine |
Article Data: | 6 |
Molecular Structure: | |
Formula: | C29H32 Cl N5 O2 |
Molecular Weight: | 518.058 |
Synonyms: | Benzo[b]-1,5-naphthyridine,phenol deriv.; Malaridine; Pyronaridine |
EINECS: | 1533716-785-6 |
Density: | 1.37g/cm3 |
Boiling Point: | 657.2oC at 760 mmHg |
Flash Point: | 351.3oC |
Solubility: | Toxicity data (The meaning of any toxicological abbreviations w">
Stability
Toxicology
Toxicity data |
Appearance: | solid |
Safety: | Moderately toxic by ingestion. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of Cl− and NOx. An antimalarial drug. |
PSA: | 76.72000 |
LogP: | 5.44880 |
IUPAC Name: 4-[(7-Chloro-2-methoxy-1,5-dihydrobenzo[b][1,5]naphthyridin-10-yl)imino]-2,6-bis(pyrrolidin-1-ylmethyl)cyclohexa-2,5-dien-1-one
The MF of Pyronaridine (CAS NO.74847-35-1) is C29H32ClN5O2.
The MW of Pyronaridine (CAS NO.74847-35-1) is 518.0497.
Synonyms of Pyronaridine (CAS NO.74847-35-1): 4-[(7-Chloro-2-methoxybenzo[b]-1,5-naphthyridin-10-yl)amino]-2,6-bis(1-pyrrolidinylmethyl)phenol ; Phenol, 4-((7-chloro-2-methoxybenzo(b)-1,5-naphthyridin-10-yl)amino)-2,6-bis(1-pyrrolidinylmethyl)-
Stability: Incompatible with strong oxidizing agents
Index of Refraction: 1.719
Apperance: solid
Density: 1.356 g/ml
Flash Point: 329.6 °C
Boiling Point: 621.3 °C
Pyronaridine (CAS NO.74847-35-1) is an antimalarial drug. It was first synthesized in 1970 and has been in clinical use in China since the 1980s.
1. | mmo-sat 100 µg/plate | CYLPDN Zhongguo Yaoli Xuebao. Acta Pharmacologica Sinica. 3 (1982),51. | ||
2. | orl-mus LD50:1100 mg/kg | YHHPAL Yaoxue Xuebao. Acta Pharmaceutica Sinica. Pharmaceutical Journal. 17 (1982),401. |
Moderately toxic by ingestion. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of Cl− and NOx. An antimalarial drug.