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78-41-1

Basic Information
CAS No.: 78-41-1
Name: TRIPARANOL
Article Data: 9
Molecular Structure:
Molecular Structure of 78-41-1 (TRIPARANOL)
Formula: C27H32 Cl N O2
Molecular Weight: 438.01
Synonyms: Ethanol,2-(p-chlorophenyl)-1-[p-[2-(diethylamino)ethoxy]phenyl]-1-p-tolyl- (6CI,8CI);1-[4-[2-(Diethylamino)ethoxy]phenyl]-1-(p-tolyl)-2-(p-chlorophenyl)ethanol;1-[p-(b-Diethylaminoethoxy)phenyl]-1-(p-tolyl)-2-(p-chlorophenyl)ethanol;2-(p-Chlorophenyl)-1-[p-(b-diethylaminoethoxy)phenyl]-1-(p-tolyl)ethanol; 2-p-Chlorophenyl-1-[p-(2-diethylaminoethoxy)phenyl]-1-p-tolylethanol;Acosterina; Clotrox; Diticyl; Drenaren; Hipocolestina; MER 29; MER 2p;Metasclene; Metasqualene; NSC 65345; Sclane; TR; Trianel; Trikosterol;Triparanol; Triparin; Tropalin; Valip; Verdiana
Density: 1.133g/cm3
Melting Point: 102.9-103.7 °C
Boiling Point: 546.9°C at 760 mmHg
Flash Point: 284.5°C
Hazard Symbols: Xn
Risk Codes: 22-41
Safety: Moderately toxic by ingestion. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits very toxic fumes of NOx and Cl.
PSA: 32.70000
LogP: 5.84760
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Chemistry

Product Name: Triparanol (CAS NO.78-41-1)


Molecular Formula: C27H32ClNO2
Molecular Weight: 438.00148g/mol
Mol File: 78-41-1.mol
Einecs: 201-115-0
Melting Point: 102.9-103.7 °C
Boiling point: 546.9 °C at 760 mmHg
Storage Temperature: 2-8°C
Flash Point: 284.5 °C
Density: 1.133 g/cm3
Solubility: DMSO: 15 mg/mL
Surface Tension: 43.7 dyne/cm
Enthalpy of Vaporization: 86.93 kJ/mol
Vapour Pressure: 8.57E-13 mmHg at 25°C
XLogP3-AA: 6.2
H-Bond Acceptor: 1
H-Bond Acceptor: 3
Product Categories: All Inhibitors; Inhibitors; Intermediates & Fine Chemicals; Pharmaceuticals

Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
rat LD50 oral 2gm/kg (2000mg/kg)   Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales. Vol. 155, Pg. 2255, 1961.

 

Safety Profile

Moderately toxic by ingestion. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits very toxic fumes of NOx and Cl.
Safety Information of Triparanol (CAS NO.78-41-1):
Hazard Codes: Xn
Risk Statements: 22-41
22:  Harmful if swallowed 
41:  Risk of serious damage to eyes
Safety Statements: 26-39
26:  In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 
39:  Wear eye/face protection

Specification

 Triparanol ,its CAS NO. is 78-41-1,the synonyms is 1-(4-(2-(Diethylamino)ethoxy)phenyl)-1-(p-tolyl)-2-(p-chlorophenyl)ethanol ; 1-(P-(beta-diethylaminoethoxy)phenyl)-1-(p-tolyl)-2-(p-chlorophenyl)ethanol ; 2-(P-chlorophenyl)-1-(p-(2-(diethylamino)ethoxy)phenyl)-1-p-tolyl-ethano ; 2-(P-chlorophenyl)-1-(p-(beta-diethylaminoethoxy)phenyl)-1-(p-tolyl)ethanol ; 2-P-chlorophenyl-1-(p-(2-diethylaminoethoxy)phenyl)-1-p-tolylethanol ; Alpha-(p-chlorobenzyl)-4-diethylaminoethoxy-4'-methylbenzhydrol ; Mer29 ; Metasqualene .