Products Categories
| CAS No.: | 79815-20-6 |
|---|---|
| Name: | (S)-(-)-Indoline-2-carboxylic acid |
| Article Data: | 19 |
| Molecular Structure: | |
|
|
|
| Formula: | C9H9NO2 |
| Molecular Weight: | 163.176 |
| Synonyms: | (S)-(-)-Indoline-2-carboxylic acid 79815-20-6;S-(-)-Indoline-2-carboxylic acid;(S)-(-) Indole-2-Carboxylic Acid;s-(-)- indoline- 2- carboxylic acid;S-Indoline-2-carboxylic acid;(S)-(-)-Indolene-2-Carboxylic Acid;S-(-)Indoline-2-carboxylic acid;(S)-Indoline-2-Carboxylic Acid;(S)-Indoline-2-formic acid;(-)-(S)-2-Indolinecarboxylic acid;(S)-(-)Indoline-2-CarboxylicAcid;(2S)-indoline-2-carboxylic acid; |
| EINECS: | 410-860-2 |
| Density: | 1.286 g/cm3 |
| Melting Point: | 177 °C (dec.)(lit.) |
| Boiling Point: | 380 °C at 760 mmHg |
| Flash Point: | 183.6 °C |
| Solubility: | Slightly soluble in water |
| Appearance: | white to light yellow crystal powder |
| Hazard Symbols: |
 Xn
|
| Risk Codes: | 43-48/22-62 |
| Safety: | 22-25-26-36/37 |
| PSA: | 49.33000 |
| LogP: | 1.24580 |
- 81281-59-67-Benzylideneaminotheophylline
- 82993-81-5D-threo-Ritalinic acid hydrochloride
- 852475-26-4MC1568
- 958254-66-51H-Imidazo[4,5-b]pyridine-2-carboxaldehyde, 1-methyl-, hydrochloride
- 99170-93-1N-Methyl-2-oxazolamine
- 914458-26-7[5-(2-fluorophenyl)-1-pentyl-1H-pyrrol-3-yl]-1-naphthalenyl-Methanone
- 894852-01-87-BROMO-2,2-DIMETHYL-2H-PYRIDO[3,2-B][1,4]OXAZIN-3(4H)-ONE
- 90221-55-92-bromo-5-methylbenzaldehyde
- 885590-99-82,3-DIFLUORO-4-IODOBENZALDEHYDE
- 97730-31-9(S)-4'-(2-Methylbutyl)Biphenyl-4-Carbonitrile
- 78779-29-0
l-(S)-2,3-dihydro-1-[(S)-3-mercapto-2-methyl-1-oxopropyl]-1H-indole-2-carboxylic acid
- 79815-20-6
(S)-indoline-2-carboxylic acid
| Conditions | Yield |
|---|---|
| With hydrogenchloride for 3h; Heating; | 100% |
- 42538-40-9
(S)-2-amino-3-(2-bromophenyl)propanoic acid
- 79815-20-6
(S)-indoline-2-carboxylic acid
| Conditions | Yield |
|---|---|
| With potassium carbonate; copper(l) chloride In 1-methyl-pyrrolidin-2-one at 80 - 100℃; for 3.5 - 4h; Product distribution / selectivity; | 95.9% |
| With potassium carbonate In water at 95℃; for 22h; Product distribution / selectivity; | 95.6% |
| With potassium carbonate; copper(l) chloride In water at 95℃; for 1h; Inert atmosphere; enantioselective reaction; | 83% |
- 141410-06-2
(S)-indoline-2-carboxylic acid methyl ester
- 79815-20-6
(S)-indoline-2-carboxylic acid
| Conditions | Yield |
|---|---|
| Stage #1: (S)-indoline-2-carboxylic acid methyl ester With sodium hydroxide; water at 20℃; Stage #2: With hydrogenchloride; water at 20℃; pH=5; | 94.5% |
- 1477-50-5
Indole-2-carboxylic acid
- 79815-20-6
(S)-indoline-2-carboxylic acid
| Conditions | Yield |
|---|---|
| With carbon disulfide; carbon dioxide; hydrogen iodide; hydrogen; potassium iodide In ethanol at 90℃; for 5h; Temperature; Solvent; Autoclave; Large scale; | 87.5% |
- 79815-20-6
(S)-indoline-2-carboxylic acid
| Conditions | Yield |
|---|---|
| With hydrogenchloride In tetrahydrofuran for 3h; Heating; | 87% |
- 110592-39-7
(S)-N-acetyl-2,3-dihydroindoline-2-carboxylic acid methyl ester
- 79815-20-6
(S)-indoline-2-carboxylic acid
| Conditions | Yield |
|---|---|
| With sulfuric acid; water Reflux; | 86.8% |
- 79815-20-6
(S)-indoline-2-carboxylic acid
| Conditions | Yield |
|---|---|
| With potassium carbonate; copper(I) bromide In water at 100 - 105℃; Inert atmosphere; | 86.2% |
- 103616-89-3
(2S)-2-amino-3-(2-chlorophenyl)propanoic acid
- 79815-20-6
(S)-indoline-2-carboxylic acid
| Conditions | Yield |
|---|---|
| With potassium carbonate; copper(l) chloride In water at 95℃; for 40h; Product distribution / selectivity; | 76.6% |
| Stage #1: (2S)-2-amino-3-(2-chlorophenyl)propanoic acid With potassium carbonate; copper(l) chloride In water at 95℃; for 40h; Stage #2: With water at 25℃; pH=3.5; Product distribution / selectivity; Acidic conditions; | 76.6% |
- 79854-38-9
(2S)-indoline-2-carboxylic acid (R)-α-methylbenzylamine salt
- 79815-20-6
(S)-indoline-2-carboxylic acid
| Conditions | Yield |
|---|---|
| With hydrogenchloride In water for 2h; Product distribution / selectivity; | 52.8% |
- 82950-72-9
1-acetyl-2,3-indoline-2-carboxylic acid
- 79815-20-6
(S)-indoline-2-carboxylic acid
| Conditions | Yield |
|---|---|
| With hydrogenchloride |
What can I do for you?
Get Best Price
Chemistry
The Molecular Structure of (S)-(-)-Indoline-2-carboxylic acid (CAS NO.79815-20-6):
Empirical Formula: C9H9NO2
Molecular Weight: 163.1733
Appearance: white to light yellow crystal powder
Nominal Mass: 163 Da
Average Mass: 163.1733 Da
Monoisotopic Mass: 163.063329 Da
Index of Refraction: 1.598
Molar Refractivity: 43.27 cm3
Molar Volume: 126.8 cm3
Surface Tension: 52.2 dyne/cm
Density: 1.286 g/cm3
Flash Point: 183.6 °C
Enthalpy of Vaporization: 66.26 kJ/mol
Boiling Point: 380 °C at 760 mmHg
Vapour Pressure: 1.88E-06 mmHg at 25°C
Refractive index: -116 ° (C=1, 2mol/L HCl)
Storage temp: Store at 0°C
Product Categories: PYRROLE;Indoles and derivatives;pharmacetical;chiral;PERINDOPRIL;(intermediate of perindopril);Indoles;Chiral Compound;Asymmetric Synthesis;Chiral Catalysts, Ligands, and Reagents;Proline-Based Organocatalysts
Uses
(S)-(-)-Indoline-2-carboxylic acid (CAS NO.79815-20-6) is mainly used in the treatment of cardiovascular and cerebrovascular diseases.
Safety Profile
Hazard Codes: 
Xn
Risk Statements: 43-48/22-62
R43: May cause sensitization by skin contact
R48/22: Harmful: danger of serious damage to health by prolonged exposure if swallowed
R62: Risk of impaired fertility
Safety Statements: 22-25-26-36/37
S22: Do not breathe dust
S25: Avoid contact with eyes
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36/37: Wear suitable protective clothing and gloves
WGK Germany: 2
Specification
(S)-(-)-Indoline-2-carboxylic acid (CAS NO.79815-20-6) is also called as (R)-1h-indole-2-carboxylic acid ; (R)-2,3-dihydro-1h-indole-2-carboxylic acid ; (R)-(+)-2,3-dihydroindole-2-carboxylic acid ; Perindopril intermediate ; (2S)-indoline-2-carboxylic acid ; (2S)-2,3-dihydro-1h-indole-2-carboxylic acid ; (S)-(-)-indoline-2-carboxylicacid98% .