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80-35-3

Basic Information
CAS No.: 80-35-3
Name: Sulfamethoxypyridazine
Article Data: 21
Molecular Structure:
Molecular Structure of 80-35-3 (Sulfamethoxypyridazine)
Formula: C11H12N4O3S
Molecular Weight: 280.307
Synonyms: Sulfanilamide,N1-(6-methoxy-3-pyridazinyl)- (7CI,8CI);3-Sulfanilamido-6-methoxypyridazine;6-Methoxy-3-pyridazinylsulfanilamide;6-Sulfanilamido-3-methoxypyridazine;Altezol;CL 13,494;CL 13494;Davosin;Davozil;Depovernil;Kinex;Kynex;LAS;LAS (pharmaceutical);Lederkin;Lederkyn;Longin;Midicel;Myasul;Paramid;Piridolo;RP 7522;Retasulfin;Sulfalex;Sulfapiridazin;
EINECS: 201-272-5
Density: 1.465 g/cm3
Melting Point: 182-183°
Boiling Point: 564.9 °C at 760 mmHg
Flash Point: 295.4 °C
Solubility: 579.5mg/L(25 oC)
Hazard Symbols: IrritantXi
Risk Codes: 37/38-41
Safety: 26-39
PSA: 115.58000
LogP: 2.60320
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Chemistry

The Molecular formula of 4-AMINO-N-(6-METHOXY-3-PYRIDAZINYL)-BENZENESULFONAMIDE(80-35-3): C11H12N4O3S
The Molecular Weight of 4-AMINO-N-(6-METHOXY-3-PYRIDAZINYL)-BENZENESULFONAMIDE(80-35-3): 280.3
The Molecular Structure of 4-AMINO-N-(6-METHOXY-3-PYRIDAZINYL)-BENZENESULFONAMIDE(80-35-3):
EINECS: 201-272-5
Boiling Point: 564.9 °C at 760 mmHg
Flash Point: 295.4 °C  
Index of Refraction: 1.646 
Molar Refractivity: 69.51 cm3 
Molar Volume: 191.2 cm3 
Polarizability: 27.55 10-24cm3 
Surface Tension: 75 dyne/cm 
Density: 1.465 g/cm3 
Enthalpy of Vaporization: 84.86 kJ/mol 
Vapour Pressure: 8.8E-13 mmHg at 25°C
storage temp.: 2-8°C
Merck: 13,9004
IUPAC Name: 4-amino-N-(6-methoxypyridazin-3-yl)benzenesulfonamide
Synonyms: Sulfametoxipiridazine;Sulfanilamide, N1-(6-methoxy-3-pyridazinyl)-;Sulfapyridazine;Sulfdurazin;Sulfozona;Sulphamethoxypyridazine;Sultirene;Surirene

Toxicity Data With Reference

1.   

orl-rat TDLo:1200 mg/kg (9-14D preg):TER

   SEIJBO    Senten Ijo. Congenital Anomalies. 13 (1973),7.
2.   

orl-rat TDLo:8400 mg/kg (male 6W pre):REP

   JRPFA4    Journal of Reproduction and Fertility. 81 (1987),259.
3.   

orl-rat LD50:2739 mg/kg

   ARZNAD    Arzneimittel-Forschung. Drug Research. 11 (1961),459.
4.   

orl-mus LD50:1750 mg/kg

   ARZNAD    Arzneimittel-Forschung. Drug Research. 15 (1965),1441.
5.   

ipr-mus LD50:1200 mg/kg

   RPTOAN    Russian Pharmacology and Toxicology. Translation of FATOAO. 37 (1974),223.
6.   

scu-mus LD50:4500 mg/kg

   ARZNAD    Arzneimittel-Forschung. Drug Research. 10 (1960),440.
7.   

scu-mus LD50:4500 mg/kg

   ARZNAD    Arzneimittel-Forschung. Drug Research. 10 (1960),440.

Safety Profile

Moderately toxic by ingestion and intraperitoneal routes. An experimental teratogen. Other experimental reproductive effects. See also SULFONATES. When heated to decomposition it emits very toxic fumes of NOx and SOx.
The Hazard Codes of 4-AMINO-N-(6-METHOXY-3-PYRIDAZINYL)-BENZENESULFONAMIDE(80-35-3):  Xi
The Risk Statements information of 4-AMINO-N-(6-METHOXY-3-PYRIDAZINYL)-BENZENESULFONAMIDE(80-35-3):
41:  Risk of serious damage to eyes 
37/38:  Irritating to respiratory system and skin 
The Safety Statements information of 4-AMINO-N-(6-METHOXY-3-PYRIDAZINYL)-BENZENESULFONAMIDE(80-35-3):
26:  In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 
39:  Wear eye/face protection 
WGK Germany: 2
RTECS: WP0400000
F: 10