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80471-63-2

Basic Information
CAS No.: 80471-63-2
Name: EPOSTANE
Molecular Structure:
Molecular Structure of 80471-63-2 (EPOSTANE)
Formula: C22H31 N O3
Molecular Weight: 357.54
Synonyms: 4,5-Epoxy-5H-cyclopenta[a]phenanthrene,androst-2-ene-2-carbonitrile deriv.; Epostane; Win 32729
Density: 1.24g/cm3
Melting Point: 191-194°
Boiling Point: 495°C at 760 mmHg
Flash Point: 253.2°C
Safety: Human toxic effects by ingestion. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx.
PSA: 76.78000
LogP: 4.24708
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    Other names:Win-32729. Systematic name:(2alpha,4alpha,5alpha,17beta)-4,5-Epoxy-17-hydroxy-4,17-dimethyl-3-oxoandrostane-2-carbonitrile

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Chemistry

Epostane(80471-63-2)'s molecular formula is C22H31NO3  and its formula weight is 357.49 .
Epostane(80471-63-2) has a  melting point of  191-194°C.
The molecular structure of epostane(80471-63-2):

Uses

Epostane(80471-63-2) is used as 3β-hydroxysteroid dehydrogenase competitive inhibitor, and for contragestive agent, which inhibits abortion caused by synthesis of the ovary  and placental progesterone.

Toxicity Data With Reference

1.   

orl-wmn TDLo:96 mg/kg

   CCPTAY    Contraception. 35 (1987),111.

Safety Profile

Human toxic effects by ingestion. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx.