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Basic Information
CAS No.: 82-45-1
Name: 1-Amino anthraquinone
Molecular Structure:
Molecular Structure of 82-45-1 (1-Amino anthraquinone)
Formula: C14H9NO2
Molecular Weight: 223.231
Synonyms: Anthraquinone,1-amino- (8CI);1-Amino-9,10-anthracenedione;1-Amino-9,10-anthraquinone;1-Aminoanthraquinone;1AAQ;9,10-Dioxo-9,10-dihydro-1-anthraceneamine;NSC30415;NSC 458;Smoke Orange G;a-Aminoanthraquinone;a-Anthraquinonylamine;
EINECS: 201-423-5
Density: 1.383 g/cm3
Melting Point: 253-255 °C(lit.)
Boiling Point: 464.9 °C at 760 mmHg
Flash Point: 235 °C
Solubility: 312.5ug/L(25 oC)
Appearance: deep brown crystalline powder
Risk Codes: 36/37/38
Safety: 24/25
PSA: 60.16000
LogP: 2.62540
Synthetic route
82-34-8

1-nitroanthraquinone

82-45-1

1-amino-9,10-anthracenedione

Conditions
ConditionsYield
With sodium hydrogensulfide99.3%
With sodium sulfide; water; sulfur at 90 - 105℃; for 6h; Temperature;98.9%
With hydrogen In water at 45 - 95℃; under 4500.45 - 6000.6 Torr; Catalytic behavior; Temperature; Autoclave; Alkaline conditions; Industrial scale;97.2%
64-19-7

acetic acid

3-(anthraquinon-1-yl)-1-(2,3,4-tri-O-acetyl-β-D-xylopyranosyl)triazene

A

62446-93-9

1,2,3,4-tetra-O-acetyl-D-xylopyranose

B

82-45-1

1-amino-9,10-anthracenedione

Conditions
ConditionsYield
for 1h; Product distribution; acetolysis; Heating;A 94%
B 99%
5960-64-5

1-(benzylamino)-9,10-anthraquinone

A

82-45-1

1-amino-9,10-anthracenedione

B

1157-84-2

1-benzylidene-2-(2,4-dinitrophenyl)hydrazone

Conditions
ConditionsYield
With sulfuric acid at 100℃; for 0.666667h;A 98%
B n/a
5960-64-5

1-(benzylamino)-9,10-anthraquinone

119-26-6

(2,4-dinitro-phenyl)-hydrazine

A

82-45-1

1-amino-9,10-anthracenedione

B

1157-84-2

1-benzylidene-2-(2,4-dinitrophenyl)hydrazone

Conditions
ConditionsYield
With sulfuric acid 1) 100 deg C, 40 min, 2) benzene, ethanol; Multistep reaction;A 98%
B n/a
concentrated sodium hydroxide

concentrated sodium hydroxide

3274-19-9

1-(acetylamino)anthraquinone

82-45-1

1-amino-9,10-anthracenedione

Conditions
ConditionsYield
In water98%
In ethanol95.2%
In methanol95%
70730-89-1

6H-anthra<1,9-cd>isoxazol-6-one

110-58-7

1-pentanamine

A

82-45-1

1-amino-9,10-anthracenedione

B

70730-79-9

3-amylaminoanthra<1,9-c,d>isoxazol-6-one

C

70730-73-3

5-amylaminoanthra<1,9-c,d>isoxazol-6-one

Conditions
ConditionsYield
With air In acetonitrile for 3.5h; Product distribution; other reagent, other solvent, other time;A n/a
B 96%
C n/a
129-43-1

1-hydroxyanthraquinone

79-07-2

Chloroacetamide

82-45-1

1-amino-9,10-anthracenedione

Conditions
ConditionsYield
With potassium carbonate; potassium iodide In N,N-dimethyl-formamide at 90 - 150℃; for 25h;87%
42013-62-7

1-azidoanthracene-9,10-dione

82-45-1

1-amino-9,10-anthracenedione

Conditions
ConditionsYield
With methanol; sodium sulfide for 0.0166667h;85%
Multi-step reaction with 2 steps
1: 79.7 percent / toluene / 0.17 h / 70 °C
2: 73 percent / 90percent H2SO4 / 1 h / 40 °C
View Scheme
82-34-8

1-nitroanthraquinone

31230-17-8

3-methyl-5-aminopyrazole

A

82-45-1

1-amino-9,10-anthracenedione

B

137267-17-5

2-methyl-8H-pyrazolo<5,1-b>benzoperimidin-8-one

Conditions
ConditionsYield
With potassium carbonate In sulfolane at 150℃; for 9h;A 13%
B 77%
212834-58-7

9,9-di(cyclohexylamino)-1-cyclohexylaminohydroxyphosphorylamino-10-anthrone

82-45-1

1-amino-9,10-anthracenedione

Conditions
ConditionsYield
With sulfuric acid for 0.25h; Hydrolysis;76%
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    Name: 1-Aminoanthraquinone CAS:82-45-1 MF: C14H9NO2 Appearance:Red crystalline powder Storage:Store in cool and dry place, away from sun light. Package: 25kgs/drum Application:Dye Intermediates Transportation:By sea or by air Port:Qingdao Port

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Chemistry

IUPAC Name: 1-Aminoanthracene-9,10-dione
CAS: 82-45-1          
Formula : C14H9NO2
Molecular Weight: 223.23
Molecular Structure of 1-Aminoanthracene-9,10-dione (82-45-1):

Density: 1.383 g/cm3 
Flash Point: 235 °C
Melting Point: 253-255 °C(lit.)
Boiling Point: 464.9 °C at 760 mmHg
Index of Refraction: 1.707 
Molar Refractivity: 62.9 cm3 
Molar Volume: 161.3 cm3 
Polarizability: 24.93×10-24cm3 
Surface Tension: 67.6 dyne/cm  
Enthalpy of Vaporization: 72.64 kJ/mol 
Vapour Pressure: 8.04E-09 mmHg at 25°C 
Water Solubility: 1.643 (mg/L) at 25°C
Appearance: deep brown crystalline powder 
Product Categories: intermediates of dyes and pigments;anthraquinones, hydroquinones and quinones;organics;aminoanthraquinones;anthraquinones;a;stains and dyes;stains&dyes, a to;C13 to C14;carbonyl compounds;ketones.

Toxicity Data With Reference

1.    

eye-rbt 100 mg/24H MOD

    28ZPAK    Sbornik Vysledku Toxixologickeho Vysetreni Latek A Pripravku Marhold, J.V.,Institut Pro Vychovu Vedoucicn Pracovniku Chemickeho Prumyclu Praha,Czechoslovakia.: 1972,121
2.    

dnd-mus-ipr 250 mg/kg

    ATSUDG    Archives of Toxicology(Suppl 5),(1982),355.
3.    

ipr-rat LD50:1500 mg/kg

    GTPZAB    Gigiena Truda i Professionalnye Zabolevaniia. Labor Hygiene and Occupational Diseases. 21 (12)(1977),27.
4.    

ipr-mus LD50:6026 mg/kg

    GTPZAB    Gigiena Truda i Professionalnye Zabolevaniia. Labor Hygiene and Occupational Diseases. 9 (3)(1965),20.

Consensus Reports

Reported in EPA TSCA Inventory.

Safety Profile

Moderately toxic by intraperitoneal route. An eye irritant. Questionable carcinogen with experimental tumorigenic data. Mutation data reported. When heated to decomposition it emits toxic NOx. See also AMINES.
Safety Information about 1-Aminoanthracene-9,10-dione (82-45-1):
Risk Statements about 1-Aminoanthracene-9,10-dione (82-45-1):
R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements about 1-Aminoanthracene-9,10-dione (82-45-1):
S24/25: Avoid contact with skin and eyes.
WGK Germany: 1
RTECS: CB5075000
HS Code: 29223900

Specification

  The chemical synonyms of 1-Aminoanthracene-9,10-dione (82-45-1) are 10-Anthracenedione,1-Amino-9 ; 1-Amino-10-anthracenedione ; 1-Amino-9,10-anthraquinone ; 1-Aminoanthra-9,10-quinone ; 1-Aminoanthrachinon ; 1-Amino-anthraquinon .It may cause eye irritation.May cause skin irritation.May be harmful if absorbed through the skin.May cause irritation of the digestive tract.May be harmful if swallowed.May cause respiratory tract irritation. May be harmful if inhaled.Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.Store in a cool, dry place. Store in a tightly closed container.It can be used as intermediate for the dispersion, reduction, active and acid dyes.