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82-66-6

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Basic Information
CAS No.: 82-66-6
Name: DIPHACINONE
Article Data: 7
Molecular Structure:
Molecular Structure of 82-66-6 (DIPHACINONE)
Formula: C23H16 O3
Molecular Weight: 340.378
Synonyms: 1,3-Indandione,2-(diphenylacetyl)- (6CI,7CI,8CI); 1H-Indene-1,3(2H)-dione, 2-(diphenylacetyl)-(9CI); 2-(Diphenylacetyl)indan-1,3-dione; Didandin; Didion; Dipaxin; Diphacin;Diphacinon; Diphacinone; Diphenacin; Diphenadion; Diphenadione; NSC 9138;Oragulant; Pestoff ferret paste; Ratindan; Ratindan 1; Solvan; U 1363
Density: 1.273g/cm3
Melting Point: 146-147°
Boiling Point: 528.7°C at 760 mmHg
Flash Point: 228.5°C
Solubility: 0.3 mg l-1
Hazard Symbols: Prevents blood clotting.
Risk Codes: 28-48/23/24/25
Safety: Poison by ingestion. Inhibits blood clotting, leading to hemorrhages. Action similar to coumadin (warfarin). A pesticide used in rodent control. When heated to decomposition it emits acrid smoke and irritating fumes.
PSA: 51.21000
LogP: 4.08300
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Chemistry

Chemical Name: Diphacinone
IUPAC NAME: 2-(2,2-Diphenylacetyl)indene-1,3-dione
CAS No.: 82-66-6
EINECS: 201-434-5
RTECS: NK5600000
Molecular Formula: C23H16O3
Molecular Weight: 340.37 g/mol
Density: 1.273 g/cm3 
Flash Point: 228.5 °C
Boiling Point: 528.7 °C at 760 mmHg
Following is the structure of Diphenadione (82-66-6):


Product Categories about are Indane/Indanone and Derivatives ; Alpha sort ; D ; DAlphabetic ; DIO - DIZPesticides&Metabolites ; Pesticides ; Pesticides&Metabolites ; Rodenticides
The chemical synonymous of are 2-(Diphenylacetyl)-1,3-diketohydrindene ; 2-Diphenylacetyl-1,3-indandione ; 2-(2,2-Diphenylacetyl)indan-1,3-dione ;  Diphacin ; Diphacinone ; Diphenadione ; 1,3-Indandione, 2-(diphenylacetyl)-

Uses

 Diphenadione (82-66-6) is a vitamin K antagonist which has anticoagulant effects and is used as a rodenticide.

Toxicity Data With Reference

1.    

orl-rat LD50:1500 µg/kg

    85DPAN    Wirksubstanzen der Pflanzenschutz und Schadlingsbekampfungsmittel Werner Perkow, Berlin, Germany.: Verlag Paul Parey,1971/76
2.    

ihl-rat LC50:2 g/m3/4H

    PEMNDP    Pesticide Manual. 9 (1991),310.
3.    

orl-mus LD50:28,300 µg/kg

    NNGADV    Nippon Noyaku Gakkaishi. 17 (1992),S319.
4.    

orl-dog LD50:3 mg/kg

    28ZEAL    Pesticide Index. 5 (1976),84.
5.    

orl-cat LD50:15 mg/kg

    PCOC**    Pesticide Chemicals Official Compendium ,Association of the American Pesticide Control Officials, Inc.(Topeka, KS.: 1966)429.
6.    

orl-rbt LD50:35 mg/kg

    85DPAN    Wirksubstanzen der Pflanzenschutz und Schadlingsbekampfungsmittel Werner Perkow, Berlin, Germany.: Verlag Paul Parey,1971/76
7.    

orl-pig LD50:150 mg/kg

    28ZEAL    Pesticide Index. 5 (1976),84.
8.    

orl-mam LD50:910 µg/kg

    SCIEAS    Science. 177 (1972),806.

Consensus Reports

EPA Extremely Hazardous Substances List.

Safety Profile

Poison by ingestion. Inhibits blood clotting, leading to hemorrhages. Action similar to coumadin (warfarin). A pesticide used in rodent control. When heated to decomposition it emits acrid smoke and irritating fumes.
Hazard Codes:
T+: Very toxic
Risk Statements about Diphenadione (82-66-6):
R28 Very toxic if swallowed.
R23/24/25: Toxic by inhalation, in contact with skin and if swallowed.
Safety Statements about Diphenadione (82-66-6):
S45 In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S36/37: Wear suitable protective clothing and gloves.