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83-73-8

Basic Information
CAS No.: 83-73-8
Name: 8-Quinolinol,5,7-diiodo-
Article Data: 24
Cas Database
Molecular Structure:
Molecular Structure of 83-73-8 (8-Quinolinol,5,7-diiodo-)
Formula: C9H5I2NO
Molecular Weight: 396.954
Synonyms: Rafamebin;SS578;Searlequin;Searlewuin;Sebaquin;Stanquinate;Yodoxin;Zoaquin;5,7-Diiodo-8-hydroxyquinoline;5,7-Diiodooxine;8-Hydroxy-5,7-diiodoquinoline;Di-Quinol;Diamoebin;Diiodohydroxyquin;Diiodohydroxyquinoline;Diiodoquin;Diiodoquinol;Dinoleine;Diodohydroxyquin;Diodoquin;Diodoxylin;Direxiode;Disoquin;
EINECS: 201-497-9
Density: 2.491 g/cm3
Melting Point: >200 °C (dec.)(lit.)
Boiling Point: 401.8 °C at 760 mmHg
Flash Point: 196.8 °C
Solubility: N/A
Appearance: N/A
Hazard Symbols: HarmfulXn
Risk Codes: 22-41
Safety: 26-36/37/39
Transport Information: N/A
PSA: 33.12000
LogP: 3.14960
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Chemistry

Molecular Structure of DIIODOHYDROXYQUIN(83-73-8):

IUPAC Name:5,7-diiodoquinolin-8-ol
Molecular Formula:C9H5I2NO
Molecular Weight:396.951040 g/mol
Melting Point:>200 °C (dec.)(lit.)
Density:2.491 g/cm3
Flash Point:196.8 °C
Enthalpy of Vaporization:67.83 kJ/mol
Boiling Point:401.8 °C at 760 mmHg
Vapour Pressure:4.96E-07 mmHg at 25 °C
Water Solubility:4.695 mg/L at 25 °C
EINECS:201-497-9
Synonyms of DIIODOHYDROXYQUIN(83-73-8):
5,7-Diiodo-8-quinolinol;IODOQUINOL;EMBEQUIN;DIIODOHYDROXYQUIN;DIIODOHYDROXYQUINOLINE;5,7-DIIODO-8-HYDROXYQUINOLINE;5,7-DIIODO-8-QUINOLINOL;5,7-DIIODOOXINE;10doquinol
Categories of DIIODOHYDROXYQUIN(83-73-8):
Quinolines, Quinazolines and derivatives;Haloquinolines;Hydroxyquinolines;Quinolines

Uses

DIIODOHYDROXYQUIN(83-73-8) widely known by the trade name diodoquin can be used in the treatment of amoebiasis.

Toxicity Data With Reference

1.   

dnr-esc 260 nmol/plate

   MUREAV    Mutation Research. 188 (1987),111.
2.   

mnt-mus-orl 80 mg/kg

   MUREAV    Mutation Research. 222 (1989),219.
3.   

orl-chd TDLo:120 g/kg/2Y-I:EYE

   LANCAO    Lancet. 1 (1966),261.
4.   

ivn-mus LD50:56 mg/kg

   CSLNX*    U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) NX#03304 .
5.   

orl-cat LDLo:300 mg/kg

   AJTMAQ    American Journal of Tropical Medicine. 24 (1944),29.
6.   

orl-gpg LDLo:50 mg/kg

   AJTMAQ    American Journal of Tropical Medicine. 24 (1944),29.

Consensus Reports

Reported in EPA TSCA Inventory.

Safety Profile

The safety information of DIIODOHYDROXYQUIN(83-73-8) is as follows:
Hazard Codes:Xn
Risk Statements:22-41
22:Harmful if swallowed
41:Risk of serious damage to eyes
Safety Statements:26-36/37/39
26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36/37/39:Wear suitable protective clothing, gloves and eye/face protection
RIDADR:3249
WGK Germany:3
RTECS:VC5775000
HazardClass:6.1(b)
PackingGroup:III
Poison by ingestion and intravenous routes. Human systemic effects by ingestion: eye effects. Mutation data reported. When heated to decomposition it emits very toxic fumes of I and NOx.

Specification

Storage information of DIIODOHYDROXYQUIN(83-73-8):
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.