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| CAS No.: | 9001-62-1 |
|---|---|
| Name: | Lipase |
| Article Data: | 2 |
| Molecular Structure: | |
|
|
|
| Formula: | Unspecified |
| Molecular Weight: | 238.19783 |
| Synonyms: | ABSFungal Lipase L;Lipase PF;Lipase PL 266;Lipase PLG;Lipase PN;Lipase PS;Lipase PS Amano SD;Acid lipase;Adipose triglyceride lipase;Alfamalt LP 10066;Allzyme Lipase;Altus 13;Altus 2;Amano AP;Amano AY 1;Amano B;Amano CE;Amano CES;Amano I;Amano II;Amano LPL 200S;Amano M;Amano N-AP;Amano P;Amano PS 30;Arthrobacter lipase;Bakezyme PH 800;Bile salt-activated lipase;Bioprase OP 10;Butyrinase;Buzyme 2517;Cacordase;Capalase;Capalase K;Capalase L;Cartazyme LP;Chirazyme 435;Chirazyme L;Chirazyme L 1;Chirazyme L 10;Chirazyme L 2;Chirazyme L2C2;Chirazyme L 3;Chirazyme L 5;Chirazyme L 6;Chirazyme L 7;Chirazyme L 8;Chirazyme L 9;Chirazyme c-f;ChiroCLEC-CAB;ChiroCLEC-CR;ChiroCLEC-PC;Cleanase NLA-P;CloneZyme ESL 001;E.C.3.1.1.3;Enzylon PF;Fetipase;Fluozim G 3Kh;GA 56;GA 56(enzyme);Glycerol ester hydrolase;Greasex;Greasex 100L;ICR-107;ICR-113;Italase;Italase C;Lilipase A 10;Lilipase A 10FG;Lilipase A 5;Lilipase B 2;Lillipase A-10FG;Lipase;Lipase A;Lipase A 100L;Lipase A 10FG;Lipase AH;Lipase AK Amano;Lipase AKG;Lipase ALC;Lipase ALG;Lipase AP;Lipase AS;Lipase AY;Lipase AY 30;Lipase AY Amano 6;Lipase CE;Lipase CR;Lipase D Amano 2000;Lipase D Amano 350;Lipase EU-034;Lipase GC Amano 4;Lipase L Amano 10;Lipase LAK;Lipase LP;Lipase LP 'S';Lipase M 10;Lipase M-AP 10;Lipase MY;Lipase OF;Lipase OFEX;Lipase PA; |
| EINECS: | 232-619-9 |
| Density: | 1.2 |
| Solubility: | H2O: 2 mg/mL |
| Appearance: | yellow-brown solution |
| Hazard Symbols: |
 B, Xn
|
| Risk Codes: | 20/21/22 |
| Safety: | 22-24/25-36/37-36 |
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Specification
The systematic name of Lipase is Lipase of Rhizopus arrhizus var. Delemar. With the CAS registry number 9001-62-1, it is also named as Accelerase. The product's categories are Hydrolases; Specialty Enzymes; Enzyme Class Index; Others; HydrolasesEnzyme Class Index; Novozymes: Quality Environmentally-Friendly EnzymesEnzyme Class Index; Analytical Enzymes; Diagnostic and Analytical EnzymesApplication Index; 3.1.x.x Acting on esters; 3.x.x.x Hydrolases; Application Index; Enzymes, Inhibitors, and Substrates; Organic Synthesis and Immobilized Enzymes; Organic SynthesisEnzyme Class Index; Enzyme-Mediated Synthesis; Specialty Synthesis; Diagnostic and Analytical EnzymesSpecialty Synthesis; HydrolasesApplication Index, and the other registry numbers are 119663-46-6; 132823-04-2; 135105-44-1; 142615-72-3; 211049-96-6; 211049-97-7; 211255-77-5; 212955-16-3; 9001-70-1; 9004-01-7; 9014-49-7. Besides, it is yellow-brown solution, which was soluble in water and hazy with insoluble particles. But it is moisture sensitive and incompatible with strong oxidizing agents. In addition, this chemical should be sealed in brown glass bottle which was stored in dry place below 4 °C.
Preparation of Lipase: this chemical is prepared by pig pancreas. Please degrease 3 kg pig pancreas which was triturated by Chloroform and Butanol. And then you should extract it by Ethanol. Finally, please freeze drying it to get 365 g Lipase.
Uses of Lipase: it is used as enzyme preparation. And it is mainly used for producing of cheese, lipid modification and hydrolysis to prevent alteration of fat in some dairy products and chocolate. Additionally, the product is a lipase of mycete which is used for washing of clothes, industry and utensils.
When you are using this chemical, please be cautious about it as the following: it is harmful by inhalation, in contact with skin and if swallowed. You should wear suitable protective clothing and gloves to avoid contact with skin and eyes. Moreover, please do not breathe dust.
The toxicity data is as follows:
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| guinea pig | LD50 | intravenous | 135mg/kg (135mg/kg) | BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION KIDNEY, URETER, AND BLADDER: OTHER CHANGES | Pharmaceutical Chemistry Journal Vol. 13, Pg. 906, 1979. |
| mouse | LD | oral | > 10400mg/kg (10400mg/kg) | Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 69, Pg. 191, 1973. | |
| mouse | LD50 | intraperitoneal | 395mg/kg (395mg/kg) | SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) SKIN AND APPENDAGES (SKIN): HAIR: OTHER | Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 69, Pg. 191, 1973. |
| mouse | LD50 | intraperitoneal | 833mg/kg (833mg/kg) | BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION BLOOD: HEMORRHAGE | Pharmaceutical Chemistry Journal Vol. 13, Pg. 906, 1979. |
| mouse | LD50 | intravenous | 127mg/kg (127mg/kg) | BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION KIDNEY, URETER, AND BLADDER: OTHER CHANGES | Pharmaceutical Chemistry Journal Vol. 13, Pg. 906, 1979. |
| mouse | LD50 | subcutaneous | 2050mg/kg (2050mg/kg) | SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) SKIN AND APPENDAGES (SKIN): HAIR: OTHER | Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 69, Pg. 191, 1973. |
| rabbit | LD | oral | > 5gm/kg (5000mg/kg) | SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) SKIN AND APPENDAGES (SKIN): HAIR: OTHER | Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 69, Pg. 191, 1973. |
| rat | LD | oral | > 10400mg/kg (10400mg/kg) | Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 69, Pg. 191, 1973. | |
| rat | LD | subcutaneous | > 5gm/kg (5000mg/kg) | SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE SKIN AND APPENDAGES (SKIN): HAIR: OTHER BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 69, Pg. 191, 1973. |
| rat | LD50 | intraperitoneal | 630mg/kg (630mg/kg) | BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION BLOOD: HEMORRHAGE | Pharmaceutical Chemistry Journal Vol. 13, Pg. 906, 1979. |
| rat | LD50 | intraperitoneal | 634mg/kg (634mg/kg) | SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) SKIN AND APPENDAGES (SKIN): HAIR: OTHER | Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 69, Pg. 191, 1973. |
| rat | LD50 | intravenous | 104mg/kg (104mg/kg) | BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION KIDNEY, URETER, AND BLADDER: OTHER CHANGES | Pharmaceutical Chemistry Journal Vol. 13, Pg. 906, 1979. |