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9001-73-4

Basic Information
CAS No.: 9001-73-4
Name: Papain
Molecular Structure:
Molecular Structure of 9001-73-4 (Papain)
Formula: Unspecified
Molecular Weight: 226.23246
Synonyms: Adolph'sMeat Tenderizer;Arbuz;Caroid;Collupulin;E.C. 3.4.22.2;E.C. 3.4.4.10;Fermizyme V 100;Liquipanol;Nematolyt;Panol II;Papain 300;Papain 6000;Papain M-40;Papain W 40;Papainase;Papaine;Papase;Papayaze;Papayotin;Pro-Fix 500;Profix 200L;Profix 6500;Profix Conc;Summetrin;Tromasin;Velardon;Vermizym;Vinozym P;
EINECS: 232-627-2
Density:
Melting Point:
Boiling Point:
Flash Point: 29 °C
Solubility: Soluble in water, insoluble in most organic solvents.
Appearance: Fine off-white powder
Hazard Symbols: R36/37/38:; R42:;
Risk Codes: Xn
Safety: 36-36/37-26-24-22-45-23-36/37/39
Transport Information:
PSA: 0.00000
LogP: 0.00000
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Chemistry

Product Name: Papain
EINECS: 232-627-2
Storage temp.: 2-8°C
Form of Papain (CAS NO.9001-73-4): lyophilized powder 
Appearance of Papain (CAS NO.9001-73-4): cream to light brown powder
Product Categories of Papain (CAS NO.9001-73-4): Enzymes; Biochemicals Found in Plants; Nutrition Research; ProteaseApplication Index; 3.4.x.x Peptidases; 3.x.x.x Hydrolases; Application Index; Proteases & Protein Sequencing; ProteasesEnzyme Class Index

Toxicity Data With Reference

1.    

orl-man TDLo:71 mg/kg:GIT

    JCGADC    Journal of Clinical Gastroenterology. 9 (1987),127.
2.    

orl-mus LD50:12,500 mg/kg

    NYKZAU    Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. 51 (1955),27.
3.    

ipr-mus LDLo:50 mg/kg

    TOXIA6    Toxicon. 19 (1981),851.

Consensus Reports

Reported in EPA TSCA Inventory.

Safety Profile

Poison by intraperitoneal route. Human systemic effects by ingestion: changes in structure or function of esophagus. Experimental teratogenic and reproductive effects. An allergen. When heated to decomposition it emits toxic fumes of NOx.
Hazard Codes: Xn
Xn:Harmful
Risk Statements  42/43-42-36/37/38
42/43:May cause sensitization by inhalation and skin contact 
42:May cause sensitization by inhalation
36/37/38:Irritating to eyes, respiratory system and skin 
Safety Statements 36-36/37-26-24-22
36:Irritating to the eyes
36/37:Irritating to eyes and respiratory system
26:Very Toxic by inhalation
24:Toxic in contact with skin 
22:Harmful if swallowed
WGK Germany:3
RTECS:RU4950000

Specification

 Papain, its cas register number is 9001-73-4. It also can be called Velardon ; and Vermizym . Its classification code are Drug / Therapeutic Agent; Enzyme [proteolytic]; Human Data; Natural Product; Reproductive Effect and TSCA Flag XU [Exempt from reporting under the Inventory Update Rule].
 Papain (CAS NO.9001-73-4) could be stable at room temperature in closed containers under normal storage and handling conditions. It should avoid the condition like incompatible materials, dust generation, excess heat, strong oxidants. It is not compatible with strong oxidizing oxidizers. And also prevent it to broken down into hazardous decomposition products: carbon monoxide in cases of incomplete combustion, carbon dioxide. However, its hazardous polymerization will not occur.

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