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| CAS No.: | 9001-84-7 |
|---|---|
| Name: | Phospholipase A2 |
| Molecular Structure: | |
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|
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| Formula: | NULL |
| Molecular Weight: | 0 |
| Synonyms: | AcanthoxinA1;Agelotoxin;Cakezyme;Conodipine-M;E.C. 3.1.1.4;Lecitase;Lecitase 10L;Lecithinase A;LysoMax;Mulgatoxin;Nigroxin C1;Nigroxin C2;Nigroxin C3;Phosphatidase;Phosphatide acyl-hydrolase;Phosphatidolipase;Phospholipase A;Phospholipase III;Phospholipin;Superbin;Superbin I;Superbin II;Superbin a;Superbin b;Superbin c;Superbin d;iPLA2;Haemachatus haemachatus phospholipase A2; |
| EINECS: | 232-637-7 |
| Appearance: | off-white solid |
| Hazard Symbols: |
 Xn, Xi
|
| Risk Codes: | 36/37/38 |
| Safety: | 26-36 |
| PSA: | 0.00000 |
| LogP: | 0.00000 |
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Specification
The Phospholipase A2, with the CAS registry number 9001-84-7, is also known as Haemachatus haemachatus phospholipase A2. It belongs to the product categories of 3.x.x.x Hydrolases; Enzyme Class Index; Others. Its EINECS number is 232-637-7. What's more, its systematic name is Phospholipase A2, from Hemachatus haemachatus snake venom. Its classification code is Natural Product. It should be sealed and stored in a cool, ventilated and dry place with the temperature of 130 °C. What's more, it should be protected from light. It is enzymes that release fatty acids from the second carbon group of glycerol. It is used in egg yolk modification, it can also used to produced salad oil.
When you are using this chemical, please be cautious about it as the following:
It is irritating to eyes, respiratory system and skin. In case of contact with eyes, you should rinse immediately with plenty of water and seek medical advice. When using it, you need wear suitable protective clothing.
The toxicity data is as follows:
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intraperitoneal | 4900ug/kg (4.9mg/kg) | Toxicon. Vol. 18, Pg. 529, 1980. | |
| mouse | LD50 | intraperitoneal | 5mg/kg (5mg/kg) | Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 232, Pg. 244, 1957. | |
| mouse | LD50 | intravenous | 630ug/kg (0.63mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: CHRONIC PULMONARY EDEMA BLOOD: HEMORRHAGE | Biochemical Pharmacology. Vol. 29, Pg. 1565, 1980. |
| mouse | LD50 | intravenous | 7500ug/kg (7.5mg/kg) | Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 230, Pg. 538, 1957. | |
| mouse | LD50 | intravenous | 8600ug/kg (8.6mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: CHRONIC PULMONARY EDEMA BLOOD: HEMORRHAGE | Biochemical Pharmacology. Vol. 29, Pg. 1565, 1980. |
| mouse | LD50 | subcutaneous | 1200ug/kg (1.2mg/kg) | Toxicon. Vol. 24, Pg. 1001, 1986. | |
| mouse | LDLo | unreported | 1mg/kg (1mg/kg) | Toxicon. Vol. 13, Pg. 90, 1975. | |
| rat | LD50 | intracrebral | 2500ng/kg (0.0025mg/kg) | Toxicon. Vol. 24, Pg. 679, 1986. | |
| rat | LD50 | parenteral | 1286ng/kg (0.001286mg/kg) | BEHAVIORAL: ANTICONVULSANT | Toxicon. Vol. 19, Pg. 61, 1981. |
| rat | LD50 | parenteral | 43ug/kg (0.043mg/kg) | LUNGS, THORAX, OR RESPIRATION: CHRONIC PULMONARY EDEMA BLOOD: HEMORRHAGE BLOOD: AGRANULOCYTOSIS | Biochemical Pharmacology. Vol. 29, Pg. 1565, 1980. |