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Basic Information
| CAS No.: | 9002-92-0 |
|---|---|
| Name: | Polyoxyethylene lauryl ether |
| Molecular Structure: | |
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| Formula: | C12H25O.(C2H4O)n |
| Molecular Weight: | 1199.54000 |
| Synonyms: | Glycols,polyethylene, monododecyl ether (8CI);Dodecyl alcohol, monoether withpolyethylene glycol (8CI);40L;40L (polyether);Actinol L 3;Actinol L 5;Actinol L 7;Adeka Carpol MBF 100;Adekatol LA 1275;Adekatol LA 50;AdekatolLA 775;Adekatol LA 875;Adekatol LB 103;Aduxol LH 05;Aethoxysklerol;Aetoxisclerol;Agrimul NRE-C12 EO5;Akyporox RLM 160;Akyporox RLM 22;AkyporoxRLM 230;Akyporox RLM 40;Aldosperse L 9;Alkasurf LAN 1;Alkasurf LAN 3;Arapol 0712;Arylpon F;Atlas G 2133;Atlas G 3705;Atlas G 3707;Atlas G 4829;Atmer 135;B 205;BL 2;BL 9 (polyglycol);Base LP 12;Blaunon EL 1502.2;Blaunon EL 1509;Brij 23;Brij 30ICI;Brij 35;Brij 35P;Brij 36T;Carsonol L 2;Chemal LA 23;Chimipal AE 3;Conion 275-100;Conion275-30;Conion 275-90;Conion 2P80;D 10;DDAE 5;DKS-NL 110;DKS-NL 150;DKS-NL180;DKS-NL 450;DKS-NL 60;DKS-NL 70;Decanol 5EO;Disperbyk 187;Disponil3065;Do 9;Dobanox 23E;EM 150 (polyether);ET 102;Eleminol NL 100;Emalex 703;Emalex 707;Emalex 710;Emalex 715;Emalex725;Emalex 750;Emalex E 709;Emergen 109P;Emulgen 100;Emulgen 103;Emulgen 105;Emulgen 108;Emulgen 109P;Emulgen 121;Emulgen 130K;Emulgen 147;Emulgen 504K;Emulmin HL 100;Emulmin L 380;Emulmin L 90S;Emulmin NL 110;Emulmin NL 70;Emulmin NL 90;SINOPOL 1150;Ethxylated C12-14 Alcohols;Polyethoxylated fatty alcohols; |
| EINECS: | 226-097-1 |
| Density: | 0.99g/mL±0.002g/mLat 20°C |
| Melting Point: | 41-45°C(lit.) |
| Boiling Point: | 100°C(lit.) |
| Flash Point: | >230°F |
| Solubility: | soluble |
| Appearance: | Clear oily liquid |
| Hazard Symbols: | R22:; R36/37/38:; |
| Risk Codes: | Xn:Harmful; ">  Xn:Harmful; |
| Safety: | 26-39-37/39-36/37/39-36-24/25 |
| PSA: | 232.52000 |
| LogP: | 4.28140 |
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Polyoxyethylene lauryl ether
Consensus Reports
Reported in EPA TSCA Inventory.
Specification
The Polyethoxylated fatty alcohols, with the CAS registry number 9002-92-0,is also known as Polyoxyethylene lauryl ether; Dodecyl polyglycol ether. It belongs to the product categories of Cell Lysis and Protein Extraction Reagents;Core Bioreagents;Research Essentials. This chemical's molecular formula is C12H25O.(C2H4O)n. What's more,Its systematic name is Ethoxylated lauryl alcohol.It is a liquid which is stable,combustible,incompatible with strong oxidizing agents.And it is a high HLB, ethoxylated, nonionic ether of lauryl alcohol with broad pH stability. It is suggested for use as emulsifier in cosmetics to add body and texture (humectant) and in household products.
Safety Information of Polyethoxylated fatty alcohols:
The Polyethoxylated fatty alcohols is harmful if swallowed and risk of serious damage to eyes .It is irritating to eyes, respiratory system and skin .In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.When you use it ,wear suitable protective clothing, gloves and eye/face protection and avoid contact with skin and eyes .
The toxicity data of Polyethoxylated fatty alcohols are as follows:
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| guinea pig | LD50 | intravenous | 38mg/kg (38mg/kg) | BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) KIDNEY, URETER, AND BLADDER: HEMATURIA LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES | Arzneimittel-Forschung. Drug Research. Vol. 7, Pg. 162, 1957. |
| guinea pig | LD50 | oral | 384mg/kg (384mg/kg) | PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES | Arzneimittel-Forschung. Drug Research. Vol. 7, Pg. 162, 1957. |
| mouse | LD50 | intraperitoneal | 160mg/kg (160mg/kg) | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 22, Pg. 967, 1991. | |
| mouse | LD50 | intraperitoneal | 160mg/kg (160mg/kg) | Drugs in Japan Vol. -, Pg. 1300, 1995. | |
| mouse | LD50 | intravenous | 100mg/kg (100mg/kg) | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 22, Pg. 967, 1991. | |
| mouse | LD50 | intravenous | 100mg/kg (100mg/kg) | Toxicology and Applied Pharmacology. Vol. 7, Pg. 206, 1965. | |
| mouse | LD50 | oral | 1170mg/kg (1170mg/kg) | Toxicology and Applied Pharmacology. Vol. 2, Pg. 133, 1960. | |
| mouse | LD50 | oral | 1170mg/kg (1170mg/kg) | PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES | Arzneimittel-Forschung. Drug Research. Vol. 7, Pg. 162, 1957. |
| mouse | LD50 | oral | 3500mg/kg (3500mg/kg) | American Perfumer and Cosmetics. Vol. 77, Pg. 35, 1962. | |
| mouse | LD50 | oral | 4940mg/kg (4940mg/kg) | American Perfumer and Cosmetics. Vol. 77, Pg. 35, 1962. | |
| mouse | LD50 | subcutaneous | 792mg/kg (792mg/kg) | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 22, Pg. 967, 1991. | |
| mouse | LD50 | subcutaneous | 792300ug/kg (792.3mg/kg) | Drugs in Japan Vol. -, Pg. 1300, 1995. | |
| rabbit | LD50 | intratracheal | > 15mg/kg (15mg/kg) | Arzneimittel-Forschung. Drug Research. Vol. 26, Pg. 78, 1976. | |
| rabbit | LD50 | intravenous | 36mg/kg (36mg/kg) | KIDNEY, URETER, AND BLADDER: HEMATURIA LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) | Arzneimittel-Forschung. Drug Research. Vol. 7, Pg. 162, 1957. |
| rabbit | LD50 | parenteral | > 75mg/kg (75mg/kg) | Arzneimittel-Forschung. Drug Research. Vol. 26, Pg. 78, 1976. | |
| rat | LD50 | intraperitoneal | 125mg/kg (125mg/kg) | GASTROINTESTINAL: OTHER CHANGES | Food and Cosmetics Toxicology. Vol. 8, Pg. 125, 1970. |
| rat | LD50 | intravenous | 27mg/kg (27mg/kg) | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 22, Pg. 967, 1991. | |
| rat | LD50 | intravenous | 27mg/kg (27mg/kg) | Drugs in Japan Vol. -, Pg. 1300, 1995. | |
| rat | LD50 | intravenous | 390mg/kg (390mg/kg) | Toxicology and Applied Pharmacology. Vol. 2, Pg. 133, 1960. | |
| rat | LD50 | oral | 1gm/kg (1000mg/kg) | LIVER: FATTY LIVER DEGERATION GASTROINTESTINAL: OTHER CHANGES GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH | Food and Cosmetics Toxicology. Vol. 8, Pg. 125, 1970. |
| rat | LD50 | oral | 4150mg/kg (4150mg/kg) | Toxicology and Applied Pharmacology. Vol. 2, Pg. 133, 1960. | |
| rat | LD50 | oral | 8600mg/kg (8600mg/kg) | Soap, Perfumery & Cosmetics. Vol. 38, Pg. 47, 1965. | |
| rat | LD50 | oral | 8600mg/kg (8600mg/kg) | Soap, Perfumery & Cosmetics. Vol. 38, Pg. 47, 1965. | |
| rat | LD50 | subcutaneous | 953mg/kg (953mg/kg) | Drugs in Japan Vol. -, Pg. 1300, 1995. | |
| rat | LD50 | subcutaneous | 954mg/kg (954mg/kg) | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 22, Pg. 967, 1991. |