CAS No.9014-01-1,EC 3.4.21.14 Suppliers,MSDS download

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Basic Information

Molecular Structure:
CAS No.:	9014-01-1
Name:	EC 3.4.21.14

Formula:	Unspecified
Molecular Weight:	0
Synonyms:	ALK-enzyme;Alcalase;Alcalase 2.0M;Alcalase 2.4L;Alcalase 2.5L;Alcalase 2.5L-DX;Alkalase AF 2.4;BLAP S;Bacillopeptidase B;Bacillus subtilisalk. proteinase;Bacillus subtilisalkaline proteinase;Bioprase;Bioprase AL 15;Bioprase Conc;Bioprase PN 4;Bioprase SP 10;Bioprase SP 20;Bioprotease B10L;ChiroCLEC CRO;Colistinase;E.C. 3.4.21.14;E.C. 3.4.4.16;Esperase 6.0T;Esperase 8.0;Evertase 24 LDP;Genenase;KAP protease;Kazusase;Maxacal CX600K;Maxatase;Nagarse;Nicotianalisin;Novozym FM;Orientase 10B;Ovozyme 24T;Peptidase, subtilo-, A;Profezym;Prolyve 1000;Properase 1000E;Protease N AmanoG;Protease VIII;Savinase TM;Serine alkaline protease;
EINECS:	232-752-2
Density:	1.3
Solubility:	100g/L at 25℃
Hazard Symbols:	Xn,N
Risk Codes:	37/38-41-42-36/37/38-50-22
Safety:	23-24-26-36/37/39-22-36/37-61-45-39
PSA:	0.00000
LogP:	0.00000

Synthetic route

: 2170-03-8
itaconic acid anhydride

subtilisin: subtilisin

vinylated subtilisin: vinylated subtilisin

Conditions

Conditions	Yield
With sodium hydroxide In phosphate buffer for 0.5h; pH=7.8; Acylation;

subtilisin: subtilisin

: 1218-34-4
N-AcTrp

subtilisin imprinted with N-acetyl-L-tryptophan: subtilisin imprinted with N-acetyl-L-tryptophan

Conditions

Conditions	Yield
In phosphate buffer at 0℃; for 0.5h; pH=7.8; Substitution;

subtilisin: subtilisin

: 2280-01-5
N-acetyl-D-tryptophan

subtilisin imprinted with N-acetyl-D-tryptophan: subtilisin imprinted with N-acetyl-D-tryptophan

Conditions

Conditions	Yield
In phosphate buffer at 0℃; for 0.5h; pH=7.8; Substitution;

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Consensus Reports

Reported in EPA TSCA Inventory.

Standards and Recommendations

ACGIH TLV: CL 0.00006 mg/m³

Specification

The Subtilisin, with the CAS registry number 9014-01-1,is also known as Bacillopeptidase A. It belongs to the product categories of Hydrolases;Specialty Enzymes.Its EINECS number is 232-752-2. What's more,Its systematic name is Subtilisin.It is a serine endopeptidase isolated from Bacillus subtilis. It hydrolyzes proteins with broad specificity for peptide bonds, and a preference for a large uncharged residue in P1. It also hydrolyzes peptide amides. (From Enzyme Nomenclature, 1992) EC 3.4.21.62.It can be produced by submerged fermentation of Bacillus licheniformis (Baeillus licheni formis).

Safety Information of Subtilisin:
The Subtilisin is risk of serious damage to eyes,and irritating to eyes, respiratory system and skin .It may cause sensitization by inhalation,so do not breathe gas/fumes/vapor/spray (appropriate wording to be specified by the manufacturer) .In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.When you use it,wear suitable protective clothing, gloves and eye/face protection.And avoid comtact with skin.

Uses of Subtilisin:
The Subtilisin can be used as proteolytic enzymes.And it is mainly used for gelatin production, and can significantly reduce the extraction time. It is also used in vegetable protein, animal protein and fish protein hydrolysis.Besides,a commercial raw proteolytic enzyme used in laundry detergents.