Products Categories
CAS No.: | 91-40-7 |
---|---|
Name: | N-Phenylanthranilic acid |
Article Data: | 142 |
Molecular Structure: | |
Formula: | C13H11NO2 |
Molecular Weight: | 213.236 |
Synonyms: | Anthranilicacid, N-phenyl- (6CI,7CI,8CI);2-(Phenylamino)benzoic acid;2-Anilinobenzoicacid;2-Carboxydiphenylamine;Diphenylamine-2-carboxylic acid;Fenamic acid;N-Phenyl-2-aminobenzoic acid;N-Phenyl-o-aminobenzoic acid;NSC 215211;NSC 4273;o-(Phenylamino)benzoic acid;o-Anilinobenzoic acid;o-Carboxydiphenylamine;N-Phenylanthranilic acid; |
EINECS: | 202-066-8 |
Density: | 1.269 g/cm3 |
Melting Point: | 182-185 °C(lit.) |
Boiling Point: | 385.2 °C at 760 mmHg |
Flash Point: | 186.7 °C |
Solubility: | insoluble in water |
Appearance: | Light grey-green to yellow-green fine powder |
Hazard Symbols: | Xi |
Risk Codes: | 36/37/38 |
Safety: | 26-36-24/25 |
PSA: | 49.33000 |
LogP: | 3.20140 |
Conditions | Yield |
---|---|
With copper(l) iodide; potassium carbonate In water; N,N-dimethyl-formamide at 100℃; for 1h; Microwave irradiation; | 100% |
With potassium hydroxide; copper In water for 9h; Heating; | 97% |
With sodium acetate; copper (I) acetate In water for 0.5h; Heating; | 97% |
Conditions | Yield |
---|---|
With copper(I) sulfate; potassium carbonate; copper(II) sulfate In water for 0.0833333h; Ullmann condensation; microwave irradiation; | 98% |
With potassium carbonate; copper(II) sulfate for 0.025h; Ullmann condensation; microwave irradiation; | 98% |
With sodium acetate; copper (I) acetate In water for 4h; Heating; | 91% |
Conditions | Yield |
---|---|
With sodium acetate; copper (I) acetate In water for 2.5h; Heating; | 94% |
With D-myo-inositol; copper; caesium carbonate In water at 100℃; for 24h; | 93% |
With potassium carbonate; copper(I) oxide; copper In 2-ethoxy-ethanol at 130℃; for 24h; | 86% |
2-phenylaminobenzonitrile
2-(phenylamino)benzoic acid
Conditions | Yield |
---|---|
With water at 25℃; for 1.5h; Reflux; | 92.2% |
Methyl N-phenylanthranilate
2-(phenylamino)benzoic acid
Conditions | Yield |
---|---|
With lithium hydroxide; water In tetrahydrofuran; methanol at 20℃; for 12h; | 82% |
Stage #1: Methyl N-phenylanthranilate With potassium hydroxide In ethanol; water for 3h; Inert atmosphere; Reflux; Stage #2: With hydrogenchloride In ethanol; water pH=2; Inert atmosphere; | 76% |
With water; potassium hydroxide In ethanol at 100℃; Inert atmosphere; | 57% |
Stage #1: Methyl N-phenylanthranilate With potassium hydroxide In ethanol; water at 20 - 100℃; Inert atmosphere; Stage #2: With hydrogenchloride In water at 0℃; pH=2; Inert atmosphere; | 57% |
Conditions | Yield |
---|---|
With di-tert-butyl{2′-isopropoxy-[1,1′-binaphthalen]-2-yl}phosphane; potassium hydroxide; bis(dibenzylideneacetone)-palladium(0) In tert-butyl alcohol at 90℃; for 20h; Inert atmosphere; | 81% |
aniline
diethylene glycol
2-bromobenzoic-acid
A
2-(phenylamino)benzoic acid
Conditions | Yield |
---|---|
With copper(II) acetate monohydrate; potassium carbonate at 110℃; for 8h; Inert atmosphere; | A 68% B 13% |
methyl 2-(methylamino)-2-oxoacetate
N-phenyl isatoic anhydride
2-(phenylamino)benzoic acid
Conditions | Yield |
---|---|
With sodium hydride In N,N-dimethyl-formamide for 0.5h; | 65% |
Conditions | Yield |
---|---|
With sodium nitrite In chloroform for 5h; Heating; | 1.5% |
methyl 2-(N-phenylbenzamido)benzoate
2-(phenylamino)benzoic acid
Conditions | Yield |
---|---|
With alkaline solution |
What can I do for you?
Get Best Price
N-Phenylanthranilic Acid, with the CAS NO.91-40-7, is a molecule which serves as a parent structure for several non-steroidal anti-inflammatory drugs, including mefenamic acid, tolfenamic acid, flufenamic acid, and meclofenamic acid. It is also named as LABOTEST-BB LT00053431; FENAMIC ACID; DIPHENYLAMINE-2-CARBOXYLIC ACID; 2-ANILINOBENZOIC ACID; 2-(PHENYLAMINO)BENZOIC ACID; 2,2'-IMINODIBENZOIC ACID; AKOS AU36-M185. The molecular formula of N-Phenylanthranilic acid is C13H11NO2 and its formula weight is C13H11NO2.
Physical properties about N-Phenylanthranilic Acid are: (1)ACD/LogP: 4.384; (2)ACD/LogD (pH 5.5): 2.66; (3)ACD/LogD (pH 7.4): 1.36; (4)ACD/BCF (pH 5.5): 23.88; (5)ACD/BCF (pH 7.4): 1.19; (6)ACD/KOC (pH 5.5): 109.18; (7)ACD/KOC (pH 7.4): 5.44; (8)#H bond acceptors: 3; (9)#H bond donors: 2; (10)#Freely Rotating Bonds: 3; (11)Index of Refraction: 1.667; (12)Molar Refractivity: 62.557 cm3; (13)Molar Volume: 168.004 cm3; (14)Polarizability: 24.8 10-24cm3; (15)Surface Tension: 57.556999206543 dyne/cm; (16)Density: 1.269 g/cm3; (17)Flash Point: 186.735 °C; (18)Enthalpy of Vaporization: 66.865 kJ/mol; (19)Boiling Point: 385.155 °C at 760 mmHg
When you are using this chemical, please be cautious about it as the following:
1. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice;
2. Wear suitable protective clothing;
3. Avoid contact with skin and eyes;
You can still convert the following datas into molecular structure:
(1)InChI=1S/C13H11NO2/c15-13(16)11-8-4-5-9-12(11)14-10-6-2-1-3-7-10/h1-9,14H,(H,15,16);
(2)InChIKey=ZWJINEZUASEZBH-UHFFFAOYSA-N;
(3)Smilesc1(c(cccc1)C(O)=O)Nc1ccccc1
The toxicity data is as follows:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intraperitoneal | 235mg/kg (235mg/kg) | Russian Pharmacology and Toxicology Vol. 37, Pg. 105, 1974. | |
mouse | LD50 | intravenous | 160mg/kg (160mg/kg) | Yakugaku Zasshi. Journal of Pharmacy. Vol. 89, Pg. 1392, 1969. |