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919797-20-9

Basic Information
CAS No.: 919797-20-9
Name: 25I-NBOH HCL
Article Data: 4
Molecular Structure:
Molecular Structure of 919797-20-9 (25I-NBOH HCL)
Formula: C17H20INO3
Molecular Weight: 413.255
Synonyms: NBOH-2CI;25I-NBOH;25I-NBOH HCL;Cimbi-27;
Density: 1.493±0.06 g/cm3(Predicted)
Boiling Point: 497.0±45.0 °C(Predicted)
PSA: 50.72000
LogP: 3.73720
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  • high quality 25I-NBOH HCL quick shipment CAS 919797-20-9

  • Casno:

    919797-20-9

    high quality 25I-NBOH HCL quick shipment CAS 919797-20-9

    Min.Order: 1 Kilogram

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  • Casno:

    919797-20-9

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Specification

25I-NBOH (NBOH-2CI, Cimbi-27, 2-C-I-NBOH) is a derivative of the phenethylamine derived hallucinogen 2C-I that was discovered in 2006 by a team at Purdue University. It acts as a potent agonist for the 5HT2A receptor, with a Ki of 0.061nM at the human 5HT2A receptor, similar to the better-known compound 25I-NBOMe, making it some twelve times the potency of 2C-I itself. In vitro tests showed this compound acted as an agonist but animal studies have not been reported. While the N-benzyl derivatives of 2C-I were significantly increased in binding activity to 5HT2A receptor fragments, compared to 2C-I, the N-benzyl derivatives of DOI were less active, compared to DOI.
25I-NBOH is notable as one of the most selective agonist ligands for the 5-HT2A receptor with an EC50 value of 0.074 nM and more than 400x selectivity over the 5-HT2C receptor.