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969-33-5

Basic Information
CAS No.: 969-33-5
Name: CYPROHEPTADINE HYDROCHLORIDE
Article Data: 2
Molecular Structure:
Molecular Structure of 969-33-5 (CYPROHEPTADINE HYDROCHLORIDE)
Formula: C21H21N.HCl
Molecular Weight: 323.865
Synonyms: Piperidine,4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-1-methyl-, hydrochloride (8CI,9CI);Ciplactin;Nuran;Periactin;Periactin hydrochloride;Periactin syrup;Peritol;Practin;Triactin;VUFB 3511;
EINECS: 213-535-1
Melting Point: 254-256.5 °C(Solv: ethanol (64-17-5); ethyl ether (60-29-7))
Boiling Point: 440.1 °C at 760 mmHg
Flash Point: 194.5 °C
Hazard Symbols: HarmfulXn
Risk Codes: 22-36/37/38
Safety: 26-36
Transport Information: UN 2811 6.1/PG 3
PSA: 3.24000
LogP: 5.43780
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    969-33-5 - Physico-chemical Properties Molecular Formula C21H22ClN Molar Mass 323.86 Melting Point 254-256.5 °C(Solv: ethanol (64-17-5); ethyl ether (60-29-7)) Solubility ethanol: soluble

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Chemistry

Product Name: Cyproheptadine hydrochloride  
CAS: 969-33-5
Formula: C21H22ClN
Molecular Weight: 323.86
Molecular Structure of  Cyproheptadine hydrochloride (CAS NO.969-33-5):

Flash Point: 194.5 °C 
Enthalpy of Vaporization: 69.72 kJ/mol 
Boiling Point: 440.1 °C at 760 mmHg 
Vapour Pressure: 6.03E-08 mmHg at 25°C 
Product Categories: active pharmaceutical ingredients;serotonin receptor.

Toxicity Data With Reference

1.    

cyt-hmn:lyms 2200 µmol/L/24H-C

    ZEKIA5    Zeitschrift fuer Kinderheilkunde. 118 (1974),219.
2.    

orl-wmn TDLo:7 mg/kg/4W-C:GIT,LIV

    BMJOAE    British Medical Journal. 1 (1978),753.
3.    

orl-rat LD50:295 mg/kg

    DRUGAY    Drugs. International Journal of Current Therapeutics and Applied Pharmacology Reviews. 6 (1982),340.
4.    

ipr-rat LD50:52,400 µg/kg

    YAKUD5    Gekkan Yakuji. Pharmaceuticals Monthly. 22 (1980),375.
5.    

orl-mus LD50:69 mg/kg

    AGACBH    Agents and Actions, A Swiss Journal of Pharmacology. 4 (1974),264.
6.    

ipr-mus LD50:55,300 µg/kg

    YAKUD5    Gekkan Yakuji. Pharmaceuticals Monthly. 22 (1980),375.

Safety Profile

Poison by ingestion and intraperitoneal routes. Human systemic effects by ingestion: jaundice, liver function tests impaired, gastrointestinal effects. An experimental teratogen. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits very toxic fumes of NOx and HCl.
Safety Information about Cyproheptadine hydrochloride (CAS NO.969-33-5):
Hazard Codes: 
Xn:
Risk Statements about Cyproheptadine hydrochloride (CAS NO.969-33-5):
R22: Harmful if swallowed.
R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements about Cyproheptadine hydrochloride (CAS NO.969-33-5):
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36: Wear suitable protective clothing.
RIDADR: UN 2811 6.1/PG 3
WGK Germany: 3
RTECS: TM7050000
HazardClass: 6.1(b)
PackingGroup: III

Specification

  The chemical synonyms of Cyproheptadine hydrochloride (CAS NO.969-33-5) are 1-Methyl-4-(5-dibenzo(a,e)cycloheptatrienylidene)piperidinehydrochloride ; 4-(5-Dibenzo(a,e)cycloheptatrienylidene)piperidinehydrochloride ; 4-(5h-Dibenzo(a,d)cyclohepten-5-ylidene)-1-methyl piperidinhydrochloride ; Cyproheptadienehydrochloride ; Nuran ; Periactinsyrup ; Periactinhydrochloride ; Periactinolhydrochloride  .