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CAS No.: | 99497-03-7 |
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Name: | Domperidone maleate |
Molecular Structure: | |
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Formula: | C22H24ClN5O2.C4H4O4 |
Molecular Weight: | 541.98 |
Synonyms: | 5-chloro-1-[1-[3-(2-oxo-3H-benzoimidazol-1-yl)propyl]-4-piperidyl]-3H-benzoimidazol-2-one;R 33,812;but-2-enedioic acid; 5-chloro-1-[1-[3-(2-oxo-3H-benzoimidazol-1-yl)propyl]-4-piperidyl]-3H-benzoimidazol-2-one;KW-5338; |
EINECS: | 801-827-7 |
Melting Point: | 236 - 239 °C |
Boiling Point: | 778.5 °C at 760 mmHg |
Flash Point: | 424.7 °C |
PSA: | 153.42000 |
LogP: | 3.00290 |
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IUPAC Name:5-Chloro-1-[1-[3-(2-oxo-1,3-dihydrobenzoimidazol-1-yl)propyl]-4-piperidyl]-1,3-dihydrobenzoimidazol-2-one maleate
Molecular Formula:C22H24ClN5O2.C4H4O4
Molecular Weight:541.99 g/mol
Melting Point:236 - 239 °C
Appearance: white powder
Domperidone maleate (CAS NO.99497-03-7) is a dopamine antagonist used as an antiemetic for the short term treatment of nausea and vomiting of various etiologies.
Toxicity: ORL-RAT LD50 5243 mg kg-1, IPR-RAT LD50 61 mg kg-1, ORL-MUS LD50 > 8000 mg kg-1 .
Domperidone maleate(99497-03-7) was determined by several methods including colorimetric methods, spectrophotometric methods, high-performance thin-layer chromatography, high-performance liquid chromatography and titrimetric methods.