1005-73-8Relevant articles and documents
Burton,Johnson
, p. 5361 (1964)
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Feast,W.J. et al.
, p. 433 - 436 (1966)
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Synthesis of hydrofluorocycloolefins through dehydrofluorination of hydrofluorocycloalkanes in amide solvents
Zhang, Wenni,Zhang, Chengping,Guo, Qin,Lu, Fengniu,Quan, Hengdao
, (2019/07/17)
Hydrofluorocycloolefins have outstanding economic and environmental advantages, as well as huge application potentials owing to their zero ozone depletion potentials (ODP) values and low global warming potentials (GWP) values. The synthesis of hydrofluorocycloolefins through dehydrofluorination of hydrohalocycloalkanes in N,N-dimethylformamide (DMF) or N,N-dimethylacetamide (DMAC) was investigated. It was found that the presence of [sbnd]CHF[sbnd] is critical for efficient elimination of HF. The reaction using reagents containing [sbnd]CHF[sbnd] group proceeded very well, whereas elimination was much more difficult to occur for reactants without [sbnd]CHF[sbnd] group. Based on these results, a rational reaction mechanism was proposed.
1H, 2H - [...] manufacturing method (by machine translation)
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Paragraph 0032-0048, (2019/08/20)
[Problem] under mild conditions, which, while satisfactorily suppressing byproduct isomers, 1H, 2H - [...] manufacturing method. (I) formula [a] (in the formula, n is an integer of 3 or more represents less than 1. ) Shown by 1H, 2H - [...] method which, in the presence of a non-water-soluble solvent, (II) the formula (where, n is an integer of 3 or more represents less than 1. ) Shown by 1H, 1H, 2H - 1 is brought into contact with the tertiary alkylamine [...] reaction steps, 1H, 2H - [...] manufacturing method. [1 A][Drawing] no (by machine translation)
Transition-Metal-Free Catalytic Hydrodefluorination of Polyfluoroarenes by Concerted Nucleophilic Aromatic Substitution with a Hydrosilicate
Kikushima, Kotaro,Grellier, Mary,Ohashi, Masato,Ogoshi, Sensuke
supporting information, p. 16191 - 16196 (2017/11/27)
A transition-metal-free catalytic hydrodefluorination (HDF) reaction of polyfluoroarenes is described. The reaction involves direct hydride transfer from a hydrosilicate as the key intermediate, which is generated from a hydrosilane and a fluoride salt. The eliminated fluoride regenerates the hydrosilicate to complete the catalytic cycle. Dispersion-corrected DFT calculations indicated that the HDF reaction proceeds through a concerted nucleophilic aromatic substitution (CSNAr) process.