100717-76-8 Usage
Description
3-butyl-2-hydroxy-1-methylquinolin-4(1H)-one, also known as ethyl hydrogen 6-keto-2-methyl-4-hydroxyquinoline-3-carboxylate or Coenzyme Q3, is a chemical compound with potent antioxidant properties. It is a derivative of Coenzyme Q, which plays a crucial role in the electron transport chain for cellular respiration. 3-butyl-2-hydroxy-1-methylquinolin-4(1H)-one has been extensively studied for its potential therapeutic applications in treating diseases associated with mitochondrial dysfunction, such as cardiovascular disease and neurodegenerative disorders. Its ability to protect cells from oxidative stress and prevent damage caused by free radicals makes it a promising candidate for various health and cosmetic applications.
Uses
Used in Pharmaceutical Applications:
3-butyl-2-hydroxy-1-methylquinolin-4(1H)-one is used as a therapeutic agent for treating diseases related to mitochondrial dysfunction, such as cardiovascular disease and neurodegenerative disorders. Its antioxidant properties help protect cells from oxidative stress and prevent damage caused by free radicals, making it a promising candidate for improving mitochondrial function and overall health.
Used in Cosmetic Formulations:
In the cosmetic industry, 3-butyl-2-hydroxy-1-methylquinolin-4(1H)-one is used as an antioxidant and anti-aging ingredient. Its ability to neutralize free radicals and protect cells from oxidative damage contributes to its potential in reducing the signs of aging and promoting skin health.
Used in Nutraceutical Applications:
3-butyl-2-hydroxy-1-methylquinolin-4(1H)-one is used as a nutraceutical supplement to support overall health and well-being. Its antioxidant properties and potential to improve mitochondrial function make it a valuable addition to dietary supplements aimed at promoting cardiovascular health and cognitive function.
Used in Research Applications:
In the field of scientific research, 3-butyl-2-hydroxy-1-methylquinolin-4(1H)-one is used as a research tool to study the role of Coenzyme Q and its derivatives in cellular respiration, mitochondrial function, and the pathophysiology of various diseases. Its potential applications in drug development and therapeutic interventions make it an important compound for ongoing research in the biomedical sciences.
Check Digit Verification of cas no
The CAS Registry Mumber 100717-76-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,0,7,1 and 7 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 100717-76:
(8*1)+(7*0)+(6*0)+(5*7)+(4*1)+(3*7)+(2*7)+(1*6)=88
88 % 10 = 8
So 100717-76-8 is a valid CAS Registry Number.
100717-76-8Relevant articles and documents
A simple and effective method for the reduction of acyl substituted heterocyclic 1,3-dicarbonyl compounds to alkyl derivatives by zinc - acetic acid - hydrochloric acid
Kappe, Thomas,Aigner, Rudolf,Roschger, Peter,Schnell, Barbara,Stadlbauer, Wolfgang
, p. 12923 - 12928 (1995)
3-Acyl-4-hydroxy-2(1H)-quinolones (1a-k) were reduced in good yields (66-97%) to 3-alkyl-4-hydroxy-2(1H)-quinolinones (2a-k) using zinc powder (particle size 〈45 μm) in acetic acid/hydrochloric acid. This method could be transformed to 3-acetyl-4-hydroxy-
Reaction of Tertiary 2-Chloroketones with Cyanide Ions: Application to 3-Chloroquinolinediones
Bedná?, Luká?,Kafka, Stanislav,Klásek, Antonín,Ly?ka, Antonín,Rouchal, Michal,Rudolf, Ond?ej
, p. 645 - 652 (2021/07/22)
3-Chloroquinoline-2,4-diones react with cyanide ions in dimethyl formamide to give 3-cyanoquinoline-2,4-diones in small yields due to the strong hindrance of the substituent at the C-3 atom. Good yields can be achieved if the substituent at this position
Oxidative ring opening of 3-hydroxyquinoline-2,4(1H,3H)-diones into N-(α-ketoacyl)anthranilic acids Dedicated to Professor Slovenko Polanc on his 65th birthday
Kafka, Stanislav,Proisl, Karel,Ka?párková, Věra,Urankar, Damijana,Kimmel, Roman,Ko?mrlj, Janez
, p. 10826 - 10835 (2014/01/06)
N-(α-Ketoacyl)anthranilic acids were prepared by oxidative ring opening of 3-hydroxyquinoline-2,4(1H,3H)-diones by using paraperiodic acid (H5IO6) or sodium periodate (NaIO4). The optimisation of the reaction conditions is
Reaction of 3-hydroxyquinoline-2,4-diones with isocyanates and thermally induced transformation of the reaction products
Mrkvicka, Vladimir,Lycka, Antonin,Vicha, Robert,Klasek, Antonin
experimental part, p. 78 - 91 (2011/03/16)
3-Hydroxyquinoline-2,4-diones 1 react with isocyanates to give novel 1,2,3,4-tetrahydro-2,4-dioxoquinolin-3-yl (alkyl/aryl)carbamates 2 and/or 1,9b-dihydro-9b-hydroxyoxazolo[5,4-c]quinoline-2,4(3aH,5H)-diones 3. Both of these compounds are converted, by boiling in cyclohexylbenzene solution in the presence of Ph3P or 4-(dimethylamino)pyridine, to give 3-(acyloxy)-1,3-dihydro-2H-indol-2-ones 8. All compounds were characterized by IR, and 1H- and 13C-NMR spectroscopy, as well as by EI mass spectrometry. Copyright