101467-40-7 Usage
Description
A further isoquinoline alkaloid which occurs in Salsola Richteri, the base is obtained in the form of a microcrystalline powder which is readily soluble in CHC13 or EtOH but only sparingly so in C6H6 or H20. The alkaloid is soluble in aqueous alkalies but insoluble in petroleum ether. The hydrochloride crystallizes as the sesquihydrate in colourless needles, m.p. 14l-152°C. The N-benzoyl derivative has m.p. 172-4° and the O,N-dibenzoyl compound, m.p. 166-8°C. Treatment with CH2N2 gives Salsolidine (q.v.). The structure, 1:2:3:4-tetrahydro6-hydroxy-7-methoxy-l-methylisoquinoline has been confirmed by synthesis.
Uses
Salsoline (cas# 89-31-6) was identified as an analyte component in Tibetan Medicine via HPLC-Q-TOF/MS.
References
Orekhov, Proskurnina., Ber., 66,841 (1933) Orekhov, Proskurnina., ibid, 67,878 (1934) Spath, Orekhov, Kuffner., ibid, 67, 1214 (1934)
Check Digit Verification of cas no
The CAS Registry Mumber 101467-40-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,1,4,6 and 7 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 101467-40:
(8*1)+(7*0)+(6*1)+(5*4)+(4*6)+(3*7)+(2*4)+(1*0)=87
87 % 10 = 7
So 101467-40-7 is a valid CAS Registry Number.
InChI:InChI=1/C11H15NO2/c1-7-9-6-11(14-2)10(13)5-8(9)3-4-12-7/h5-7,12-13H,3-4H2,1-2H3/t7-/m1/s1
101467-40-7Relevant articles and documents
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Portnyagina et al.
, (1971)
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METABOLISM OF SALSOLINOL BY TISSUE CULTURES OF SOME PAPAVERACEAE
Iwasa, K.,Kamigauchi, M.,Takao, N.
, p. 2973 - 2976 (2007/10/02)
(+/-)-Salsolinol, a substance possibly inducing Parkinsonism and alcoholism, was transformed into the 6- and 7-O-monomethylated salsolinols by various plant tissue cultures of Papaveraceae.Only 6-O-methylsalsolinol was further N-methylated to provide N-methylisosalsoline.Key Word Index - Corydalis ochotensis; C. opliocarpa; Macleaya cordata; Papaveraceae; tissue cultures; metabolism; isoquinoline alkaloid; salsolinol.