102396-29-2

• 

• Basic information

  1. Product Name: 6-chloro-5-methyl-2-(piperazin-1-yl)-N-(propan-2-yl)pyrimidin-4-amine
  2. Synonyms: 4-pyrimidinamine, 6-chloro-5-methyl-N-(1-methylethyl)-2-(1-piperazinyl)-
  3. CAS NO:102396-29-2
  4. Molecular Formula: C₁₂H₂₀ClN₅
  5. Molecular Weight: 269.7737
  6. EINECS: N/A
  7. Product Categories: N/A
  8. Mol File: 102396-29-2.mol
  9. Article Data: 2

• Chemical Properties

  1. Melting Point: N/A
  2. Boiling Point: 458.7°C at 760 mmHg
  3. Flash Point: 231.2°C
  4. Appearance: N/A
  5. Density: 1.197g/cm³
  6. Vapor Pressure: 1.34E-08mmHg at 25°C
  7. Refractive Index: 1.576
  8. Storage Temp.: N/A
  9. Solubility: N/A
  10. CAS DataBase Reference: 6-chloro-5-methyl-2-(piperazin-1-yl)-N-(propan-2-yl)pyrimidin-4-amine(CAS DataBase Reference)
  11. NIST Chemistry Reference: 6-chloro-5-methyl-2-(piperazin-1-yl)-N-(propan-2-yl)pyrimidin-4-amine(102396-29-2)
  12. EPA Substance Registry System: 6-chloro-5-methyl-2-(piperazin-1-yl)-N-(propan-2-yl)pyrimidin-4-amine(102396-29-2)

• Safety Data

  1. Hazard Codes: N/A
  2. Statements: N/A
  3. Safety Statements: N/A
  4. WGK Germany:
  5. RTECS:
  6. HazardClass: N/A
  7. PackingGroup: N/A
  8. Hazardous Substances Data: 102396-29-2(Hazardous Substances Data)

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• Usage
• SDS
• Upstream product
• Downstream Products
• Article

102396-29-2 Suppliers

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• TIANFUCHEM-4-Pyrimidinamine,6-chloro-5-methyl-N-(1-methylethyl)-2-(1-piperazinyl)-

  Cas No: 102396-29-2

• USD $ 4230.0-4230.0 / Metric Ton

• 1 Metric Ton

• 1 Metric Ton/Day

• Henan Tianfu Chemical Co., Ltd.
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102396-29-2 Usage

General Description

6-chloro-5-methyl-2-(piperazin-1-yl)-N-(propan-2-yl)pyrimidin-4-amine, also known as GDC-0349, is a chemical compound with potential therapeutic applications. It is a pyrimidine derivative that has been studied for its potential as a kinase inhibitor for the treatment of cancer. It is designed to inhibit the activity of specific kinases involved in cancer cell proliferation and survival. GDC-0349 has shown promise in preclinical studies as a potential treatment for various types of cancer, and it may have the potential to be used in combination with other cancer therapies to improve treatment outcomes. Further research and clinical trials are needed to fully understand the potential benefits and risks of this compound for cancer treatment.

Check Digit Verification of cas no

The CAS Registry Mumber 102396-29-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,2,3,9 and 6 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 102396-29:
(8*1)+(7*0)+(6*2)+(5*3)+(4*9)+(3*6)+(2*2)+(1*9)=102
102 % 10 = 2
So 102396-29-2 is a valid CAS Registry Number.

102396-29-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name	6-chloro-5-methyl-2-piperazin-1-yl-N-propan-2-ylpyrimidin-4-amine

1.2 Other means of identification

Product number	-
Other names	2-piperazino-4-isopropylamino-5-methyl-6-chloropyrimidine

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:102396-29-2 SDS

102396-29-2Upstream product

• 84727-78-6 4-(4,6-Dichloro-5-methyl-pyrimidin-2-yl)-piperazine-1-carbaldehyde 
• 7556-55-0 1-formyl-4-methylpiperidine 
• 84727-79-7 4-(4-Chloro-6-isopropylamino-5-methyl-pyrimidin-2-yl)-piperazine-1-carbaldehyde 

102396-29-2Downstream Products

102396-29-2Relevant articles and documents

4-Amino-6-chloro-2-piperazinopyrimidines with selective affinity for α2-adrenoceptors

Gueremy,Audiau,Renault,Benavides,Uzan,Le Fur

, p. 1394 - 1398 (2007/10/02)

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