10357-07-0 Usage
General Description
N4-Benzoyl-5-fluorocytosine, also known as 4-Benzoyl-5-fluorocytosine, is a synthetic compound with potential antineoplastic and antiviral activities. It is a derivative of cytosine in which the hydrogen at position 5 is replaced with fluorine and the amino group at position 4 is linked to a benzoyl group. N4-Benzoyl-5-fluorocytosine has been investigated for its potential use in cancer therapy and antiviral treatment, with research focusing on its ability to interfere with DNA replication and protein synthesis in cancer cells and viruses. Studies have shown that N4-Benzoyl-5-fluorocytosine exhibits promising anticancer and antiviral activity, making it a potential candidate for further development and clinical evaluation.
Check Digit Verification of cas no
The CAS Registry Mumber 10357-07-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,3,5 and 7 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 10357-07:
(7*1)+(6*0)+(5*3)+(4*5)+(3*7)+(2*0)+(1*7)=70
70 % 10 = 0
So 10357-07-0 is a valid CAS Registry Number.
InChI:InChI=1/C11H8FN3O2/c12-8-6-13-11(17)15-9(8)14-10(16)7-4-2-1-3-5-7/h1-6H,(H2,13,14,15,16,17)
10357-07-0Relevant articles and documents
N -Glycosylation with sulfoxide donors for the synthesis of peptidonucleosides
Beau, Jean-Marie,Beretta, Margaux,Dr?ge, Thomas,Es-Sayed, Mazen,Nicolas, Lionel,Norsikian, Stéphanie,Rouchaud, Emilie,Vors, Jean-Pierre
supporting information, p. 4285 - 4291 (2021/05/31)
The synthesis of glycopyranosyl nucleosides modified in the sugar moiety has been less frequently explored, notably because of the lack of a reliable method to glycosylate pyrimidine bases. Herein we report a solution in the context of the synthesis of peptidonucleosides. They were obtained after glycosylation of different pyrimidine nucleobases with glucopyranosyl donors carrying an azide group at the C4 position. A methodological study involving different anomeric leaving groups (acetate, phenylsulfoxide and ortho-hexynylbenzoate) showed that a sulfoxide donor in combination with trimethylsilyl triflate as the promoter led to the best yields.