10391-47-6 Usage
Description
19-Norkaur-16-en-18-oicacid, 2,15-dihydroxy-, (2b,4a,15a)is a naturally occurring diterpenoid compound with a unique 19-norsteroid backbone. It features hydroxyl groups at positions 2 and 15, with the stereochemistry (2b,4a,15a). 19-Norkaur-16-en-18-oicacid, 2,15-dihydroxy-, (2b,4a,15a)has demonstrated various biological activities, such as anti-inflammatory and antioxidant properties, and holds potential for therapeutic applications in conditions like cancer and cardiovascular diseases. Further research is essential to explore its pharmacological potential and mechanisms of action fully.
Uses
Used in Pharmaceutical Industry:
19-Norkaur-16-en-18-oicacid, 2,15-dihydroxy-, (2b,4a,15a)is used as a potential therapeutic agent for its anti-inflammatory and antioxidant properties. Its ability to modulate inflammation and oxidative stress makes it a promising candidate for the treatment of various inflammatory and oxidative stress-related conditions.
Used in Cancer Therapy:
In the field of oncology, 19-Norkaur-16-en-18-oicacid, 2,15-dihydroxy-, (2b,4a,15a)is being investigated for its potential as an anticancer agent. Its biological activities suggest that it may have the capacity to target cancer cells, inhibit tumor growth, and enhance the effectiveness of conventional cancer treatments. Further research is needed to understand its specific mechanisms of action in cancer therapy.
Used in Cardiovascular Disease Management:
19-Norkaur-16-en-18-oicacid, 2,15-dihydroxy-, (2b,4a,15a)is also being explored for its potential applications in cardiovascular disease management. Its anti-inflammatory and antioxidant properties may contribute to the prevention and treatment of various cardiovascular conditions, such as atherosclerosis, hypertension, and myocardial infarction. More studies are required to determine its efficacy and safety in this context.
Check Digit Verification of cas no
The CAS Registry Mumber 10391-47-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,3,9 and 1 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 10391-47:
(7*1)+(6*0)+(5*3)+(4*9)+(3*1)+(2*4)+(1*7)=76
76 % 10 = 6
So 10391-47-6 is a valid CAS Registry Number.
10391-47-6Relevant articles and documents
Structural characterization and antimicrobial evaluation of atractyloside, atractyligenin, and 15-didehydroatractyligenin methyl ester
Brucoli, Federico,Borrello, Maria T.,Stapleton, Paul,Parkinson, Gary N.,Gibbons, Simon
, p. 1070 - 1075 (2012)
We report the first complete structure elucidation of the ent-kaurane diterpenoid glycoside atractyloside (1) by means of NMR and X-ray diffractometry techniques. Extensive one- and two-dimensional NMR experiments were employed to assign the proton and carbon signals of 1, and crystallography experiments established the configurations of all stereogenic centers. Furthermore, we present a novel semisynthetic route for the preparation of the highly cytotoxic aglycone derivative of 1, 15-didehydroatractyligenin methyl ester (3). All compounds were tested for their antibiotic activity against Enterococcus faecalis, Escherichia coli, and several strains of Staphylococcus aureus, including fluoroquinoloneresistant (SA1199B) and two epidemic MRSA (EMRSA-15 and -16) strains. Compound 3 exhibited moderate activity against all of the Staph. aureus strains with an MIC value of 128 mg/L.
