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105281-06-9

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105281-06-9 Usage

General Description

1-(2,5-dideoxy-2-fluoro-beta-D-arabinofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione, also known as FAMPyra or 4-aminopyridine, is a chemical compound used as a medication to improve walking in adults with multiple sclerosis (MS). It works by blocking potassium channels in nerve cells, which can improve the conduction of signals along damaged nerves. This can lead to improved muscle function and coordination, allowing for better mobility in MS patients. FAMPyra is available in tablet form and is typically taken twice a day as prescribed by a physician. It is important to follow the dosage and usage instructions carefully to avoid any potential side effects.

Check Digit Verification of cas no

The CAS Registry Mumber 105281-06-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,5,2,8 and 1 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 105281-06:
(8*1)+(7*0)+(6*5)+(5*2)+(4*8)+(3*1)+(2*0)+(1*6)=89
89 % 10 = 9
So 105281-06-9 is a valid CAS Registry Number.

105281-06-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-methyloxolan-2-yl]-5-methylpyrimidine-2,4-dione

1.2 Other means of identification

Product number -
Other names 5'-deoxy-FMAU

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:105281-06-9 SDS

105281-06-9Downstream Products

105281-06-9Relevant articles and documents

Nucleosides. 139. Synthesis and Anticytomegalovirus and Antiherpes Simplex Virus Activity of 5'-Modified Analogues of 2'-Fluoroarabinosylpyrimidine Nucleosides

Harada, Kazuho,Matulic-Adamic, Jasenka,Price, Richard W.,Schinazi, Raymond F.,Watanabe, Kyoichi A.,Fox, Jack J.

, p. 226 - 229 (2007/10/02)

In order to determine if modification of the 5'-position reduces or abolishes the antiviral activity of 2'-fluoro-5-iodo-ara-C (FIAC), 2'-fluoro-5-iodo-ara-U (FIAU), or 2'-fluoro-5-methyl-ara-U (FMAU) against human cytomegalovirus (HCMV) and herpes simple

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