105310-91-6Relevant articles and documents
Studies on the SAR and pharmacophore of milnacipran derivatives as monoamine transporter inhibitors
Chen, Chen,Dyck, Brian,Fleck, Beth A.,Foster, Alan C.,Grey, Jonathan,Jovic, Florence,Mesleh, Michael,Phan, Kasey,Tamiya, Junko,Vickers, Troy,Zhang, Mingzhu
, p. 1346 - 1349 (2008/09/18)
Derivatives of milnacipran were synthesized and studied as monoamine transporter inhibitors. Potent analogs were discovered at NET (9k) and at both NET and SERT (9s and 9u). A pharmacophore model was established based on the conformational analysis of mil