105512-80-9Relevant articles and documents
Substituted thiazole derivative and application thereof
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Paragraph 0153-0154; 0274-0278, (2019/02/13)
The invention provides a compound represented by a general formula (I), or a stereoisomer, pharmaceutically acceptable salt, solvate, hydrate, chemically protective form or prodrug thereof. The compound has an effect of inhibiting adenosine receptor 2a (A2a), and can be used as an antagonist of the adenosine receptor 2a (A2A) for treating tumors.
FUSED PYRIMIDINE-DIONE DERIVATIVES AS TRPA1 MODULATORS
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Page/Page column 41, (2010/11/03)
The invention described herein relates to novel fused pyrimidinediones derivatives of formula (I) which are TRPA (Transient Receptor Potential subfamily A) modulators. In particular, compounds described herein are useful for treating or preventing diseases, conditions and/or disorders modulated by TRPAl (Transient Receptor Potential subfamily A, member 1). This invention also provides processes for preparing compounds described herein, intermediates used in their synthesis, pharmaceutical compositions thereof, and methods for treating or preventing diseases, conditions and/or disorders modulated by TRPAl. Formula (I)
QUINAZOLINEDIONE DERIVATIVES AS TRPA1 MODULATORS
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Page/Page column 17, (2010/01/31)
The present invention provides Quinazolinedione derivatives as TRPA (Transient Receptor Potential subfamily A) modulators. In particular, compounds described herein are useful for treating or preventing diseases, conditions and/or disorders modulated by T