105512-88-7

• 

• Basic information

  1. Product Name: 4-(4-METHOXY-PHENYL)-5-METHYL-THIAZOL-2-YLAMINE
  2. Synonyms: TIMTEC-BB SBB001537;4-(4-METHOXY-PHENYL)-5-METHYL-THIAZOL-2-YLAMINE;2-AMINO-4-(4-METHOXYPHENYL)-5-METHYLTHIAZOLE;AURORA KA-7886;4-(4-Methoxyphenyl)-5-Methylthiazol-2-aMine;4-(4-methoxyphenyl)-5-methyl-1,3-thiazol-2-amine;2-Thiazolamine,4-(4-methoxyphenyl)-5-methyl-
  3. CAS NO:105512-88-7
  4. Molecular Formula: C₁₁H₁₂N₂OS
  5. Molecular Weight: 220.29
  6. EINECS: N/A
  7. Product Categories: N/A
  8. Mol File: 105512-88-7.mol
  9. Article Data: 5

• Chemical Properties

  1. Melting Point: N/A
  2. Boiling Point: 384.9 °C at 760 mmHg
  3. Flash Point: 186.6 °C
  4. Appearance: /
  5. Density: 1.223 g/cm³
  6. Vapor Pressure: 3.95E-06mmHg at 25°C
  7. Refractive Index: 1.618
  8. Storage Temp.: N/A
  9. Solubility: N/A
  10. PKA: 5.05±0.10(Predicted)
  11. CAS DataBase Reference: 4-(4-METHOXY-PHENYL)-5-METHYL-THIAZOL-2-YLAMINE(CAS DataBase Reference)
  12. NIST Chemistry Reference: 4-(4-METHOXY-PHENYL)-5-METHYL-THIAZOL-2-YLAMINE(105512-88-7)
  13. EPA Substance Registry System: 4-(4-METHOXY-PHENYL)-5-METHYL-THIAZOL-2-YLAMINE(105512-88-7)

• Safety Data

  1. Hazard Codes: Xi
  2. Statements: N/A
  3. Safety Statements: N/A
  4. WGK Germany:
  5. RTECS:
  6. HazardClass: IRRITANT
  7. PackingGroup: N/A
  8. Hazardous Substances Data: 105512-88-7(Hazardous Substances Data)

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• TIANFU-CHEM_105512-88-7// 4-(4-Methoxy-phenyl)-5-methyl-thiazol-2-ylamine

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• Henan Tianfu Chemical Co., Ltd.
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105512-88-7 Usage

General Description

4-(4-Methoxy-phenyl)-5-methyl-thiazol-2-ylamine is a chemical compound that belongs to the thiazole class of compounds. It is an amine derivative with a thiazole ring that contains a 4-methoxyphenyl and a 5-methyl substituent. 4-(4-METHOXY-PHENYL)-5-METHYL-THIAZOL-2-YLAMINE has potential applications in pharmaceutical research and drug development due to its structural features and properties. Thiazole derivatives have been studied for their various biological activities, including antimicrobial, antitumor, and antiviral activities, making them important compounds for drug discovery and development. The specific properties and potential uses of 4-(4-Methoxy-phenyl)-5-methyl-thiazol-2-ylamine would need to be further investigated in laboratory studies and clinical trials.

Check Digit Verification of cas no

The CAS Registry Mumber 105512-88-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,5,5,1 and 2 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 105512-88:
(8*1)+(7*0)+(6*5)+(5*5)+(4*1)+(3*2)+(2*8)+(1*8)=97
97 % 10 = 7
So 105512-88-7 is a valid CAS Registry Number.

InChI:InChI=1/C11H12N2OS/c1-7-10(13-11(12)15-7)8-3-5-9(14-2)6-4-8/h3-6H,1-2H3,(H2,12,13)

105512-88-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name	4-(4-Methoxy-phenyl)-5-methyl-thiazol-2-ylamine

1.2 Other means of identification

Product number	-
Other names	4-(4-METHOXY-PHENYL)-5-METHYL-THIAZOL-2-YLAMINE

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:105512-88-7 SDS

105512-88-7Upstream product

• 17356-08-0 thiourea 
• 121-97-1 4-Methoxypropiophenone 
• 21086-33-9 2-bromo-1-(4-methoxyphenyl)-1-propanone 

105512-88-7Downstream Products

• 1192812-96-6 N-(4-(4-methoxyphenyl)-5-methylthiazol-2yl)-1H-imidazole-1-carbothioamide 
• 1192807-29-6 N-(4-(4-methoxyphenyl)-5-methylthiazol-2-yl)-4H-1'-azaspiro[oxazole-5,3'-bicyclo[2.2.2]octan]-2-amine 
• 1192874-02-4 (2-(4-(4-methoxyphenyl)-5-methylthiazol-2-ylamino)-4H-1'-ammoniospiro[oxazole-5,3'-bicyclo[2.2.2]octane]-1'-yl)trihydroborate 
• 904925-04-8 ethyl [4-(4-methoxyphenyl)-5-methyl-1,3-thiazol-2-yl]carbamate 

105512-88-7Relevant articles and documents

Synthesis and antimicrobial activities of some novel 2,3-substituted-1,3-thiazolidin-4-ones derived from 2-amino-1,3-thiazole

Maher

, p. 2794 - 2798 (2017/11/10)

New 2,3-substituted-1,3-thiazolidin-4-one (6a-f) were prepared by cyclocondensation of 2-[6-(4-chlorobenzyloxy)-2-naphthyliden]-4-(4-substituted phenyl)-5-methyl-1,3-thiazole (5a-f) and mercaptoacetic acid in benzene. The synthesized compounds were charac

Modulators Of HEC1 Activity And Methods Therefor

-

, (2011/10/10)

Compounds, compositions, and methods for modulation of Hec1/Nek2 interaction are provided. Especially preferred compounds disrupt Nek2/Hec1 binding and are therefore useful as chemotherapeutic agent for neoplastic diseases.

TRISUBSTITUTED THIAZOLE COMPOUNDS, PREPARATIONS METHODS, PHARMACEUTICAL COMPOSITIONS AND MEDICALS USES THEREOF

-

Page/Page column 32, (2009/12/23)

The present invention relates to 2,4,5-trisubstituted thiazole compounds of formula (I) or all possible isomers, prodrugs, pharmaceutically acceptable salts, solvates or hydrates thereof for the inhibition of plasma PLTP activity and/or plasma CETP activity, wherein the substituents are as defined in the specification; a process for the preparation of the compounds of formula (I); a pharmaceutical composition comprising the compound of formula (I) and its use for the preparation of a medicament for treatment and/or prevention of diseases associated with the increased plasma PLTP activity and/or the increased plasma CETP activity in a mammal, such as atherosclerosis, cardiovascular diseases and peripheral vascular diseases, etc.

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