105538-02-1 Usage
General Description
3-Amino-6-(thiophen-3-yl)pyridazine is a heterocyclic organic compound with the molecular formula C7H6N4S. It is a derivative of pyridazine with a thiophene substitution at the 3-position and an amino group at the 6-position. This chemical compound is used in organic synthesis as a building block for creating various pharmaceuticals, agrochemicals, and biologically active compounds. It is also used as a reagent in chemical reactions for the formation of new carbon-carbon and carbon-nitrogen bonds. 3-Amino-6-(thiophen-3-yl)pyridazine has potential applications in medicinal chemistry and drug discovery due to its unique structural features and biological activities.
Check Digit Verification of cas no
The CAS Registry Mumber 105538-02-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,5,5,3 and 8 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 105538-02:
(8*1)+(7*0)+(6*5)+(5*5)+(4*3)+(3*8)+(2*0)+(1*2)=101
101 % 10 = 1
So 105538-02-1 is a valid CAS Registry Number.
InChI:InChI=1/C8H7N3S/c9-8-2-1-7(10-11-8)6-3-4-12-5-6/h1-5H,(H2,9,11)
105538-02-1Relevant articles and documents
Mild and direct access to 7-substituted-4-trifluoromethylpyrimido[1,2- b ]pyridazin-2-one systems
Petrignet, Julien,Thiery, Emilie,Silpa, Laurence,Abarbri, Mohamed
, p. 947 - 954 (2014/04/03)
New and efficient methods for the synthesis of 7-substituted-4- trifluoromethylpyrimido[1,2-b]pyridazin-2-one derivatives using either two-step Suzuki/heterocyclization, or two-step heterocyclization/substitution sequences are developed. A variety of substituted products are obtained in good to excellent yields from 3-amino-6-chloropyridazine and ethyl 4,4,4-trifluorobut-2- ynoate. Georg Thieme Verlag Stuttgart · New York.
A new approach towards the synthesis of 3-amino-6- (hetero)arylpyridazines based on palladium catalyzed cross-coupling reactions
Maes, Bert U. W.,Lemière, Guy L. F.,Dommisse, Roger,Augustyns, Koen,Haemers, Achiel
, p. 1777 - 1781 (2007/10/03)
The synthesis of 3-amino-6-(hetero)arylpyridazines via palladium catalyzed cross-coupling reactions (Suzuki, Stille) on 3-amino-6- chloropyridazine (1a) and 3-amino-6-iodopyridazine (1b) has been investigated. Comparison of the results shows that there is
