105609-36-7Relevant articles and documents
Electrochemical Decarboxylation of Hydroxyproline: A Simple Three-Step Conversion of (2S,4R)-4-Hydroxyproline to (R)-γ-Amino-β-hydroxybutanoic Acid (GABOB)
Renaud, Philippe,Seebach, Dieter
, p. 424 - 426 (2007/10/02)
A high yield conversion on preparative scale of (2S.4R)-N-acetyl-4-hydroxyproline (1) to (R)-GABOB (4) is reported.The key step of the synthesis is the electrochemical oxidative decarboxylation of 1.