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105784-82-5

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105784-82-5 Usage

Uses

3''-Azido-2'',3''-dideoxy-5-bromouridine can be used in biological study of virtual screening approach for thymidine monophosphate kinase inhibitors as antitubercular agents based on docking and pharmacophore models.

Check Digit Verification of cas no

The CAS Registry Mumber 105784-82-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,5,7,8 and 4 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 105784-82:
(8*1)+(7*0)+(6*5)+(5*7)+(4*8)+(3*4)+(2*8)+(1*2)=135
135 % 10 = 5
So 105784-82-5 is a valid CAS Registry Number.

105784-82-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-[(2R,4S,5S)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-bromopyrimidine-2,4-dione

1.2 Other means of identification

Product number -
Other names 3'-azido-5-bromo-2',3'-dideoxyuridine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:105784-82-5 SDS

105784-82-5Relevant articles and documents

Antimycobacterial activities of 5-alkyl (or halo)-3′-substituted pyrimidine nucleoside analogs

Srivastav, Naveen C.,Shakya, Neeraj,Bhavanam, Sudha,Agrawal, Amogh,Tse, Chris,Desroches, Nancy,Kunimoto, Dennis Y.,Kumar, Rakesh

supporting information; experimental part, p. 1091 - 1094 (2012/03/26)

Several 5-alkyl (or halo)-3′-azido (amino or halo) analogs of pyrimidine nucleosides have been synthesized and evaluated against Mycobacterium bovis, Mycobacterium tuberculosis and Mycobacterium avium. Among these compounds, 3′-azido-5-ethyl-2′,3′-dideoxyuridine (3) was found to have significant antimycobacterial activities against M. bovis (MIC 50 = 1 μg/mL), M. tuberculosis (MIC50 = 10 μg/mL) and M. avium (MIC50 = 10 μg/mL).

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