108561-00-8 Usage
Description
P-Cresol-d3 (Methyl-d3), also known as a deuterated form of p-cresol, is a derivative of phenol characterized by its colorless to yellow liquid appearance and a phenolic odor. P-CRESOL-D3 (METHYL-D3) is distinguished by the presence of three deuterium isotopes, which significantly enhance its utility in scientific research and analysis.
Uses
Used in Chemical Research:
P-Cresol-d3 (Methyl-d3) is used as a labeled compound for tracing and identifying p-cresol and its related compounds in chemical research. Its deuterated form provides a distinct signature in mass spectrometry, facilitating the accurate quantification and identification of target molecules.
Used in Environmental Studies:
In environmental studies, P-Cresol-d3 (Methyl-d3) serves as a tracer to monitor the presence and behavior of p-cresol in various ecosystems. The use of this deuterated compound allows for the differentiation between naturally occurring p-cresol and that which may be introduced through human activities or other sources.
Used in Biological Studies:
P-Cresol-d3 (Methyl-d3) is utilized as a tracer in biological studies to investigate the metabolism and excretion of p-cresol in living organisms. Its incorporation into biological systems aids researchers in understanding the compound's impact on health and its role in various physiological processes.
Used in Mass Spectrometry:
P-Cresol-d3 (Methyl-d3) is employed in mass spectrometry as an internal standard for the precise measurement of p-cresol concentrations. The presence of deuterium isotopes in its structure provides a stable and easily distinguishable reference point, improving the accuracy and reliability of analytical results.
Used in Pharmaceutical Development:
In the pharmaceutical industry, P-Cresol-d3 (Methyl-d3) may be used as a reference compound in the development of drugs targeting p-cresol metabolism or its associated pathways. Its unique properties can help in assessing the efficacy of new drug candidates and optimizing their pharmacological profiles.
Check Digit Verification of cas no
The CAS Registry Mumber 108561-00-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,8,5,6 and 1 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 108561-00:
(8*1)+(7*0)+(6*8)+(5*5)+(4*6)+(3*1)+(2*0)+(1*0)=108
108 % 10 = 8
So 108561-00-8 is a valid CAS Registry Number.
108561-00-8Relevant articles and documents
Method for catalytic conversion of cyano group into deuterated methyl, prepared aromatic deuterated methyl compound and application of compound
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Paragraph 0079; 0080; 0081; 0082; 0083, (2017/12/09)
The invention provides a method for catalytic conversion of a cyano group into deuterated methyl, a prepared aromatic deuterated methyl compound and an application of the compound. The method comprises the steps as follows: an aromatic cyano compound reacts to produce the aromatic deuterated methyl compound under the action of a metal catalyst with deuterium gas serving as a deuterium source. The cyano group is directly catalyzed into deuterated methyl with the deuterium gas serving as the deuterium source, the operation is simple, the raw material is cheap and easy to obtain, the reaction yield is high, the product deuteration rate is high, and the method can be applied to mass production. The prepared aromatic deuterated methyl compound can be used as a deuterated medicine or can be used for preparation of a deuterated medicine or deuterated medicine composition, and the pharmacokinetics, pharmacodynamics or metabolism toxicity of the medicine can be reduced while the medicine molecular activity is kept unchanged basically.
Deuterated Benzopyran Compounds and Application Thereof
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, (2015/05/26)
The present invention discloses deuterated benzopyran compounds having structure features as shown in Formula (I), or pharmaceutically acceptable salts or stereoisomers thereof, or prodrug molecules thereof. With excellent anti-inflammatory and analgesic effects and the capability to inhibit growth of tumor cells, such compounds are novel COX-2 selective inhibitors. The compounds and pharmaceutically acceptable salts thereof disclosed by the present application can be applied in preparing anti-inflammatory and analgesic drugs and drugs for treating or preventing tumors.
Active site dynamics of toluene hydroxylation by cytochrome P-450
Hanzlik,Ling
, p. 3992 - 3997 (2007/10/02)
Rat liver cytochrome P-450 hydroxylates toluene to benzyl alcohol plus o-, m-, and p-cresol. Deuterated toluenes (C6D5CH3, C6D5CD3, PhCD(n)H(3-n)) were incubated under saturating conditions
