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11002-13-4

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11002-13-4 Usage

Biological Functions

Human plasma contains a glycoprotein called angiotensinogen, which serves as the only known substrate for renin. Angiotensinogen must undergo proteolysis before active portions of the protein are sufficiently unmasked to exert biological effects. Angiotensinogen is synthesized in many organs, including the liver, brain, kidney, and fat. Its gene transcription and plasma concentrations increase following treatment with adrenocorticotropic hormone (ACTH), glucocorticoids, thyroid hormone, and estrogens, as well as during pregnancy and inflammation and after nephrectomy. Angiotensinogen also has been found in large quantities in cerebrospinal and amniotic fluid. Mutations in the angiotensinogen gene have been reported to be linked to human hypertension.

Check Digit Verification of cas no

The CAS Registry Mumber 11002-13-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,1,0,0 and 2 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 11002-13:
(7*1)+(6*1)+(5*0)+(4*0)+(3*2)+(2*1)+(1*3)=24
24 % 10 = 4
So 11002-13-4 is a valid CAS Registry Number.

11002-13-4Upstream product

11002-13-4Downstream Products

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