110076-61-4Relevant articles and documents
Insecticidal Activity of Novel Trihaloimidazole Derivatives against a Wild Colony of German Cockroaches (Blattella germanica)
Tomioka, Hiroki,Yano, Toshihiko,Takada, Yoji,Takeda, Hisami,Hirata, Naonori
, p. 1601 - 1606 (2007/10/02)
Structure-activity relationships of novel 1-alkoxymethyl-2,4,5-trihalimidazole compounds against a wild colony of German cockroaches resistant to pyrethroids (O-colony) are reported.Among them, 1-methoxymethyl-2-bromo-4,5-dichloroimidazole and 1-isopropoxymethyl-2-bromo-4,5-dichloroimidazole were very effective by a filter paper contact method.The variation in insecticidal activity is shown to be related to the length and branching of the alkyl chain of the 1-substituents.Above all, 1-(4-bromobutoxymethyl)-2-bromo-4,5-dichloroimidazole and 1-(4-bromo/chlorobutoxymethyl)-2,4,5-trichloroimidazole exhibited low acute oral toxicity to mice and good activity by a heating fumigant test, representing one of the practical applications.The trihaloimidazole derivatives had almost two-fold higher activity against O-colony insects than against the susceptible strain.
