11048-97-8 Usage
General Description
Hedamycin is a complex class of antibiotics that are derived from the bacterium Streptomyces griseorubiginosus. It is a highly potent chemotherapy agent with broad-spectrum activity against both solid tumor and hematological malignancies. The chemical structure of hedamycin contains two main components: a DNA-binding anthraquinone moiety and a flexible polypeptide chain. This unique structure allows it to intercalate and bind to DNA, causing inhibition of DNA synthesis and ultimately leading to cell death. Despite its cytotoxic effects, hedamycin is also known for its significant toxicity, particularly on the bone marrow, and as a result, its clinical use has been limited. However, research and interest in hedamycin as a potential anticancer agent continue due to its potent anti-tumor properties.
Check Digit Verification of cas no
The CAS Registry Mumber 11048-97-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,1,0,4 and 8 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 11048-97:
(7*1)+(6*1)+(5*0)+(4*4)+(3*8)+(2*9)+(1*7)=78
78 % 10 = 8
So 11048-97-8 is a valid CAS Registry Number.
InChI:InChI=1/C41H50N2O11/c1-16-11-22-30(37-28(16)24(44)14-27(53-37)41(6)39(54-41)36-18(3)52-36)35(48)31-29(34(22)47)20(25-13-23(42(7)8)32(45)17(2)50-25)12-21(33(31)46)26-15-40(5,43(9)10)38(49)19(4)51-26/h11-12,14,17-19,23,25-26,32,36,38-39,45-46,49H,13,15H2,1-10H3
