111150-22-2

• 

• Basic information

  1. Product Name: NF110
  2. Synonyms: NF110;4,4',4'',4'''-[Carbonylbis[imino-5,1,3-benzenetriylbis(carbonylimino)]]tetrakisbenzenesulfonicacidtetrasodiumsalt
  3. CAS NO:111150-22-2
  4. Molecular Formula: C41H28N6O17S4.4Na
  5. Molecular Weight: 1096.92
  6. EINECS: N/A
  7. Product Categories: N/A
  8. Mol File: 111150-22-2.mol
  9. Article Data: 0

• Chemical Properties

  1. Melting Point: N/A
  2. Boiling Point: N/A
  3. Flash Point: N/A
  4. Appearance: /
  5. Density: N/A
  6. Refractive Index: N/A
  7. Storage Temp.: Desiccate at RT
  8. Solubility: N/A
  9. CAS DataBase Reference: NF110(CAS DataBase Reference)
  10. NIST Chemistry Reference: NF110(111150-22-2)
  11. EPA Substance Registry System: NF110(111150-22-2)

• Safety Data

  1. Hazard Codes: N/A
  2. Statements: N/A
  3. Safety Statements: N/A
  4. WGK Germany:
  5. RTECS:
  6. HazardClass: N/A
  7. PackingGroup: N/A
  8. Hazardous Substances Data: 111150-22-2(Hazardous Substances Data)

• Suppliers
• Usage
• SDS
• Upstream product
• Downstream Products
• News

111150-22-2 Suppliers

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• NF 110

  Cas No: 111150-22-2

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• Dayang Chem (Hangzhou) Co.,Ltd.
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• Benzenesulfonic acid,4,4',4'',4'''-[carbonylbis[imino-5,1,3-benzenetriylbis(carbonylimino)]]tetrakis-,tetrasodium salt (9CI)

  Cas No: 111150-22-2

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• 10000 Metric Ton/Month

• Henan Wentao Chemical Product Co., Ltd.
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• Benzenesulfonic acid,4,4',4'',4'''-[carbonylbis[imino-5,1,3-benzenetriylbis(carbonylimino)]]tetrakis-,tetrasodium salt (9CI)

  Cas No: 111150-22-2

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• Hangzhou J&H Chemical Co., Ltd.
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• NF 110

  Cas No: 111150-22-2

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• BOC Sciences
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• NF110

  Cas No: 111150-22-2

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• ZHEJIANG JIUZHOU CHEM CO.,LTD
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• NF 110;4,4',4'',4'''-[Carbonylbis[iMino-5,1,3-benzenetriylbis(carbonyliMino)]]tetrakisbenzenesulfonicacidtetrasodiuMsalt

  Cas No: 111150-22-2

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• Wuxi Morality Chemical Co., Ltd
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• NF110

  Cas No: 111150-22-2

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• Tocris Bioscience
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111150-22-2 Usage

Uses

NF 110 is a potent P2X3 receptor antagonist.

Biological Activity

High affinity P2X 3 receptor antagonist (K i values are 36, 82 and 4144 nM for P2X 3 , P2X 1 and P2X 2 recombinant receptors respectively). Shows no activity at P2Y 1 , P2Y 2 and P2Y 11 receptors (IC 50 > 10 μ M). Potently inhibits α , β -meATP-evoked desensitizing currents in rat DRG neurons (IC 50 = 527 nM). Shows antitumor activity against several tumor types.

Check Digit Verification of cas no

The CAS Registry Mumber 111150-22-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,1,1,5 and 0 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 111150-22:
(8*1)+(7*1)+(6*1)+(5*1)+(4*5)+(3*0)+(2*2)+(1*2)=52
52 % 10 = 2
So 111150-22-2 is a valid CAS Registry Number.

111150-22-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name	NF 110,4,4',4'',4'''-[Carbonylbis[imino-5,1,3-benzenetriylbis(carbonylimino)]]tetrakisbenzenesulfonicacidtetrasodiumsalt

1.2 Other means of identification

Product number	-
Other names	NF110

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:111150-22-2 SDS

111150-22-2Upstream product

111150-22-2Downstream Products

111150-22-2Related news

ArticleMolecular mechanism underlying the subtype-selectivity of competitive inhibitor NF110 (cas 111150-22-2) and its distinct potencies in human and rat P2X3 receptors08/27/2019

P2X receptors are a family of extracellular ATP-gated trimeric cation channels that is widely distributed in human tissues. Quite some drug candidates targeting P2X receptors have entered into preclinical or main phases of clinical trials, but many of them failed due to low subtype-selectivity o...detailed

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